Dopplerometric Indicators of the Liver in Patients with Mild Pre-Eclampsia

  • Tuksanova D. I. 2-Department of Obstetrics and Gynecology, Bukhara State Medical Institute, Bukhara, Uzbekistan
Keywords: Doppler, preeclampsia, liver blood flow

Abstract

This article considers the etiopathogenetic and clinical significance of increased intra-abdominal pressure, intra-abdominal hypertension (IAH) and cardiovascular maladaptation (CVD) in the development of preeclampsia. None of the existing theories fully explains the pathogenetic mechanisms leading to the development of preeclampsia. Preeclampsia is characterized by intra-abdominal compression of the kidneys, mesenteric and pelvic vessels, venous hyperemia and, as a result, ischemia of the kidneys, uterine-fetal-placental complex, liver, and pathological activation of the renin-angiotensin system. This article provides an insight into the role of intra-abdominal hypertension in the development of a complex of hemodynamic, respiratory and renal disorders that ultimately lead to preeclampsia and multiple organ failure in pregnant women. The article discusses the Doppler signs of intra-abdominal hypertension in the prognosis of preeclampsia, characterizes the qualitative and quantitative indicators of the Doppler wave patterns of the renal and hepatic vessels.

References

1. Akhmedov F.K. Peculiarities of cardiac hemodynamic in pregnant women with mild preeclampsia// Europen Science Review. - 2015. - №4-5. - С. 56 -58.
2. Akhmedov F.K. Features of renal function and some indicators of homeostasis in women with mild preeclampsia// Europen Science Review. - 2015. - №4-5. - С. 58 - 60.
3. Akhmedov F.K., Negmatullaeva M.N., Kurbanova Z.Sh. Modern views on the problem of preeclampsia // A new day in medicine. - 2018. - № 1 (21). - S. 180-185.
4. Akhmedov F.K., Negmatullaeva M.N., Features of the state of central hemodynamics and hemostasis in pregnant women with preeclampsia of varying degrees and severity // New Day of Medicine. - 2020. - No. 1 (29) - S. 147-150.
5. Zaripova, D. YA., Negmatullaeva, M. N., Tuksanova, D. I., Ashurova, N. G. (2019). Vliyanie magnij deficitnogo sostoyaniya i disbalansa steroidnyh gormonov zhiznedeyatel'nosti organizma zhenshchiny. Tibbiyotda yangi kun, 3, 27.
6. Zaripova, D. YA., Negmatullaeva, M. N., Tuksanova, D. I., Ahmedov, F. K. (2019). Rol' Aleandronovoj kisloty (Ostalon) v lechenii perimenopauzal'nogo osteoporoza. Doktor ahborotnomasi, 4(3).
7. Manuhin I.B., Markova E.V., Markova L.I., Stryuk R.I. Kombinirovannaya nizkodozovaya antigipertenzivnaya terapiya u beremennyh s arterial'noj gipertoniej i gestozom // Kardiologiya. – 2012. – № 1. – S.32–38
8. Negmatullaeva M.N., Hamdamova, M.T, Hotamova M.T. (2022). Konservativnaya miomektomiya u zhenshchin reproduktivnogo vozrasta. ZHurnal vestnik vracha, 1(1), 62–64. https://doi.org/10.38095/2181-466X-2020931-61-63
9. Negmatullaeva, M.N., Dustova, N. K. (2012). Mochevaya kislota-marker razvitiya preeklampsii. Problemy biologii i mediciny, 1, 26.
10. Tuksanova D.I., Avakov V.E., Nazhmutdinova D.K., Negmatullaeva M.N., Ahmedov F.K. Osobennosti pochechnogo i pechenochnogo krovotoka u beremennyh s preeklampsiej. Rossijskij vestnik akushera-ginekologa. 2013;13(5):41‑43.
11. Tuksanova, D. I., SHaripova, M. A. (2018). Osobennosti izmenenij pokazatelej sistemnogo i organnogo krovotoka u zhenshchin pri tyazhyoloj preeklampsiej. Mezhdunarodnyj Kazahsko-Tureckij Universitet “Sovremennaya medicina tradicii i innovacii”. –Kazakstan, 151-155.
12. Tuksanova, D. I. (2019). Osobennosti sostoyanie parametrov gomeostaza i kardiogemodinamiki u zhenshchin s fiziologicheskim techeniem beremennosti. Novyj den' v medicine-Tibbiyotda yangi kun-2019, 1(25), 159-163.
13. Tuksanova, D. I. (2019). Features of the state of parameters of homeostasis and cardiodynamics in women with the physiological course of pregnancy. Tibbietda yangi kun. -Tashkent, (1), 25.
14. Lam C., Lim K.-H., Karumanchi S.A. Circulating Angiogenic Factors in the Pathogenesis and Prediction of Preeclampsia. Hypertension. 2005; 46:1077.
15. Chappell L.C., Shennan A.H. Assessment of proteinuria in pregnancy B.M.J., May 3, 2008; 336(7651): 968 969.
16. Myers J.E., Hart S., Armstrong S., Mires G.S., Beynon R., Simon J. Gaskell S.J., Baker P.N. Evidence for multiple circulating factors in preeclampsia. //Am. J. Obstet. Gynec. 2007. - 196 (3). - P. 266.
17. Sibai B.M. Biomarker for hypertension-preeclampsia: are we close yet? // Am.J. Obstet.Gynec.2007.-Vol.196.-№1.
18. Thangaratinam S., Coomarasamy A., Sharp S. Et al. Tests for predicting complications of pre-eclampsia: a protocol for systematic reviews. B.M.C. Pregnancy Childbirth. -2008Aug11;8(1):38.
Published
2022-07-13
How to Cite
I. , T. D. (2022). Dopplerometric Indicators of the Liver in Patients with Mild Pre-Eclampsia. Central Asian Journal of Medical and Natural Science, 3(4), 51-54. https://doi.org/10.17605/cajmns.v3i4.932
Section
Articles