Effectiveness of conservative treatment of Peyronie's disease

  • Nurillayev J.Ya. Samarkand state medical university
Keywords: Peyronie's disease, curvature, penis, fibrous plaque, deformity, erectile dysfunction, penile pain, trauma, intralesional injection, shock wave therapy

Abstract

The article is devoted to the effectiveness of conservative treatment of Peyronie's disease. As a result, it was found that the drug Potaba affects Peyronie's plaque. The drug can slightly improve the existing curvature of the penis, there is a significant protective effect, especially if the effect is pronounced with a short course of the disease. Potassium para aminobenzoate is useful in stabilizing Peyronie's disease and is needed to prevent the progression of penile curvature, which "stops" the process. The plaque does not increase, and the angle of curvature does not increase. The stabilization stage comes faster and with fewer consequences. Group B with Peyronie's disease who received a combination of oral medications (vitamin A, E) and intralesional injections of kenalog and dexamethasone showed a significant improvement in penile curvature, pain, erectile function, and patient satisfaction. These data support the potential efficacy of this approach in treating the symptoms of Peyronie's disease. Further research, including randomized controlled trials and larger sample sizes, is needed to confirm these results and establish the optimal treatment protocol for patients with this complex condition. Those who received a combination of oral preparations (vitamins A, E), intralesional injections of kenalog and dexamethasone, and extracorporeal shock wave therapy increase the effectiveness of treatment up to 55.6%. After the termination of the course of treatment, if the curvature is only cosmetic in nature and does not interfere with sexual intercourse, and does not violate the erection, then the operation is not necessary. Unfortunately, no guarantees can be made about preventing the future progression of the disease. The results of the study indicate the effect of Potaba on Peyronie's plaque. The drug can slightly improve the existing curvature of the penis, there is a significant protective effect, especially if the effect is pronounced with a short course of the disease. Potassium para aminobenzoate is useful in stabilizing Peyronie's disease and is needed to prevent the progression of penile curvature, which "stops" the process. The plaque does not increase, and the angle of curvature does not increase. The stabilization stage comes faster and with fewer consequences.

References

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Published
2023-05-27
How to Cite
Nurillayev J.Ya. (2023). Effectiveness of conservative treatment of Peyronie’s disease. Central Asian Journal of Medical and Natural Science, 4(3), 471-475. https://doi.org/10.17605/cajmns.v4i3.771
Section
Articles