Efficiency of immunomodulating therapy in acute obstructive bronchitis in children

  • Ibatova Sh.M. Samarkand State Medical Institute
  • Muhamadiev N.Q. Samarkand State University
Keywords: acute obstructive bronchitis, patients, relapse, immune status, T-activin, immunomodulatory therapy


A corrective method for the treatment of acute obstructive bronchitis is proposed, including T-activin in the complex therapy of children with acute obstructive bronchitis. In order to correct the immunological parameters, patients with ARD were prescribed T-activin subcutaneously at the rate of 2 μg / kg of body weight daily for 5 days and the sixth injection a week after injections. Clinically, all children who received T-activin showed positive dynamics with an increase in the effectiveness of treatment, which contributed to the normalization of indicators of the immune status of patients and prevented the development of relapses of the disease


Artamonov R.G. Bronchitis // Medical scientific and educational journal. - 2008. - No. 42. - S. 3-24.

Zaitseva OV Broncho-obstructive syndrome in children. Pediatrics, 2005, No.4, -S. 94-104.

Zakirova U.I. Phenotypic features of Uzbek children with obstructive bronchitis. Uzbekiston Tibbiyot magazines, 2002, No. 5. -S. 55-58.

Ibatova Sh.M., Mamatkulova F.Kh. Broncho-obstructive syndrome in children: the prevalence of differential diagnosis and prognosis. J. "Problems of Biology and Medicine". Samarkand. 2019, No. 3, -S.233-236.

Ibatova Sh.M., Mamatkulova F.Kh. The state of immunity in chronic obstructive pulmonary disease in children. F "Problems of Biology and Medicine." Samarkand, 2021, No. 1.1 (126), -S.110-1127.

Smirnova M.O., Sorokina E.V. Bronchitis in children: principles of modern therapy // Difficult patient. - 2009. - No. 8-9. - S. 19-23.

Sh.M. Ibatova, F. Kh. Mamatkulova, N. B. Abdukadirova, Yu. A. Rakhmonov, M.M. Kodirova. Risk Factors for Development of Broncho-Ostructive Syndrome in Children. International Journal of Current Research and Review. Vol 12. Issue 23 December 2020. – P. 3-6.

Ibatova Sh.M., Mamatkulova F. Kh., Ruzikulov N.Y. The Clinical Picture of Acute Obstructive Bronchitis in Children and the Rationale for Immunomodulatory Therapy. International Journal of Current Research and Review. Vol 12 Issue 17. September 2020. - P.152-155.

How to Cite
Ibatova Sh.M., & Muhamadiev N.Q. (2021). Efficiency of immunomodulating therapy in acute obstructive bronchitis in children. Central Asian Journal of Medical and Natural Science, 2(2), 210-213. https://doi.org/10.17605/cajmns.v2i2.76