Effects of Energy Drinks on Biochemical and Sperm Parameters in Albino Rats
Keywords:
Albino Rats, Energy drink, Biochemical markers, Reproductive organs
Abstract
Background: The present study evaluates the effects of energy drinks on the reproductive and biochemical parameters of adult male rats.Methods: A total. The animals were divided into four groups and exposed to increasing therapeutic doses (DT) of an energy drink, based on allometric extrapolation, resulting in values (mL/day) per animal of 250 g: DT1 2.36 mL, DT3 7.47 mL, and DT6 14.16 mL. The control group (CTRL) consumed water only. During the treatment, the rats were assessed for signs of toxicity. After treatment, the animals were sacrificed and their organs were weighed. Sperm parameters (motility, concentration, and morphology) were evaluated. The biochemical markers alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lactic dehydrogenase, urea, creatinine, creatine phosphokinase, and creatine kinase MB fraction were measured, in addition to total cholesterol and testosterone.
References
1. Muxiddinovna, I. M. (2022). IMPACT OF ENERGY DRINKS AND THEIR COMBINATION WITH ALCOHOL TO THE RATS METOBOLISM. Gospodarka i Innowacje., 22, 544-549.
2. Mukhiddinovna, I. M. (2022). EFFECTS OF CHRONIC CONSUMPTION OF ENERGY DRINKS ON LIVER AND KIDNEY OF EXPERIMENTAL RATS. International Journal of Philosophical Studies and Social Sciences, 2(4), 6-11.
3. Halimova Yu.S. Shokirov B.S. Morphological changes of internal organs in chronic alcoholism// Middle European Scientific Bulletin 12, 51-55.
4. Ю.С. Халимова, Б.С. Шокиров. (2022). СОВРЕМЕННЫЕ ДАННЫЕ О МОРФО-ФУНКЦИОНАЛЬНЫХ АСПЕКТОВ ЧЕЛОВЕЧЕСКОГО ОРГАНИЗМА ПРИ ЗЛОУПОТРЕБЛЕНИЕ ЭНЕРГЕТИЧЕСКИМИ НАПИТКАМИ// PEDAGOGS jurnali. Том 4, № 1. С. 154-161.
5. Khasanova, M. Т. (2022). HISTOPATHOLOGICAL CHANGES IN STRUCTURE OF KIDNEY UNDER THE CONSUMPTION OF ENERGYDRINKS IN RATS. International Journal of Philosophical Studies and Social Sciences, 2(2), 167-171.
6. Хасанова, М. Т., & Убайдуллаев, Ш. Ф. (2022). НАРУШЕНИЕ ПАМЯТИ У БОЛЬНЫХС СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТЬЮ. Gospodarka i Innowacje., 22, 603-607.
7. Khasanova, M. Т. (2022). Damage of Energy Drinks on Morphological Structures of Rat’s Pancreas. Spanish Journal of Innovation and Integrity. Vol 5 (2022). P. 217, 220.
8. Iyadurai SJ, Chung SS. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav. 2007;10(3):504–8.
9. Камалова, Ш. М., Тешаев, Ш. Ж., & Хамидова, Н. К. (2020). Параметры физического развития 8-летних детей в норме и при сколиозе. Морфология, 157(2-3), 92-93
10. Worrall BB, Phillips CD, Henderson KK. Herbal energy drinks, phenylpropanoid compounds, and cerebral vasculopathy. Neurology. 2005; 65(7):1137–8.
11. Dias TR, Alves MG, Bernardino RL, Martins AD, Moreira AC, Silva J, Barros A, Sousa M, Silva BM, Oliveira PF. Dose-dependent effects of caffeine in human Sertoli cells metabolism and oxidative profile: relevance for male fertility. Toxicology. 2015;328:12–20.
12. Reiter LW. Research plan for endocrine disruptors. National Service Center for Environmental Publications; 1998. http://nepis.epa.gov/Exe/ZyPURL. cgi?Dockey=10003A5G.TXT.
13. Bila DM, Dezotti M. Desreguladores endócrinos no meio ambiente: efeitos e consequências. Quim Nova. 2007;30:651–66.
14. Guide for the care and use of laboratory animals, 8th ed. Washington: National Academic Press; 2011. https://grants.nih.gov/grants/olaw/guide-for- the-care-and-use-of-laboratory-animals.pdf.
15. Pachaly JR, Fernando H, de Brito V. Interspecific allometric scaling. In: Sons JW, editor. Biology, medicine, and surgery of South American wild animals. Iowa State University Press: Wiley; 2008. p. 475–81.
16. Oshio LT, Guerra MO. Methods in toxicology of the male reproductive system and fertility in rodents. Interdisciplinary J Exp Stud. 2009;1(3):148–52.
17. Berkey CS, Rockett HR, Field AE, Gillman MW, Colditz GA. Sugar-added beverages and adolescent weight change. Obes Res. 2004;12(5):778–88.
18. Nawrot P, Jordan S, Eastwood J, Rotstein J, Hugenholtz A, Feeley M. Effects of caffeine on human health. Food Addit Contam. 2003;20(1):1–30.
19. Алимова, Н. П., & Асадова, Н. Х. (2020). Изучение анатомии через проблемное обучение среди студентов медиков. In Сборник материалов международной учебной онлайн конференции “Современное состояние медицинского образования: проблемы и перспективы (pp. 138-139).
20. Алимова, Н. П. (2021). Оценка Состояние Детей С Гипертрофий Аденоидов В Педиод Карантина. Барқарорлик ва Етакчи Тадқиқотлар онлайн илмий журнали, 1(6), 774-785.
21. Temirova, N. R. (2022). MORPHOMETRIC INDICATORS OF GROWTH AND DEVELOPMENT OF CHILDREN IN ENDEMIC AREAS. British Medical Journal, 2(1).
22. Safehood: The Food Safety Promotion Board. A review of the health effects of stimulant drinks—final report. In: Food Safety Promotion Board EA, editor. Eastgate, Little Island, Cork; 2002. http://www.safefood.eu/SafeFood/ media/SafeFoodLibrary/Documents/Publications/Research%20Reports/FSPB- Stimulant-drinks.pdf.
23. Kamalova, S. M., & Teshaev, S. J. Comparative Characteristics of Morphometric Parameters of Children with Scoliosis. measurements, 14, 15.
24. Chen W, Guo J, Zhang Y, Zhang J. The beneficial effects of taurine in preventing metabolic syndrome. Food Funct. 2016;7(4):1849–63.
2. Mukhiddinovna, I. M. (2022). EFFECTS OF CHRONIC CONSUMPTION OF ENERGY DRINKS ON LIVER AND KIDNEY OF EXPERIMENTAL RATS. International Journal of Philosophical Studies and Social Sciences, 2(4), 6-11.
3. Halimova Yu.S. Shokirov B.S. Morphological changes of internal organs in chronic alcoholism// Middle European Scientific Bulletin 12, 51-55.
4. Ю.С. Халимова, Б.С. Шокиров. (2022). СОВРЕМЕННЫЕ ДАННЫЕ О МОРФО-ФУНКЦИОНАЛЬНЫХ АСПЕКТОВ ЧЕЛОВЕЧЕСКОГО ОРГАНИЗМА ПРИ ЗЛОУПОТРЕБЛЕНИЕ ЭНЕРГЕТИЧЕСКИМИ НАПИТКАМИ// PEDAGOGS jurnali. Том 4, № 1. С. 154-161.
5. Khasanova, M. Т. (2022). HISTOPATHOLOGICAL CHANGES IN STRUCTURE OF KIDNEY UNDER THE CONSUMPTION OF ENERGYDRINKS IN RATS. International Journal of Philosophical Studies and Social Sciences, 2(2), 167-171.
6. Хасанова, М. Т., & Убайдуллаев, Ш. Ф. (2022). НАРУШЕНИЕ ПАМЯТИ У БОЛЬНЫХС СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТЬЮ. Gospodarka i Innowacje., 22, 603-607.
7. Khasanova, M. Т. (2022). Damage of Energy Drinks on Morphological Structures of Rat’s Pancreas. Spanish Journal of Innovation and Integrity. Vol 5 (2022). P. 217, 220.
8. Iyadurai SJ, Chung SS. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav. 2007;10(3):504–8.
9. Камалова, Ш. М., Тешаев, Ш. Ж., & Хамидова, Н. К. (2020). Параметры физического развития 8-летних детей в норме и при сколиозе. Морфология, 157(2-3), 92-93
10. Worrall BB, Phillips CD, Henderson KK. Herbal energy drinks, phenylpropanoid compounds, and cerebral vasculopathy. Neurology. 2005; 65(7):1137–8.
11. Dias TR, Alves MG, Bernardino RL, Martins AD, Moreira AC, Silva J, Barros A, Sousa M, Silva BM, Oliveira PF. Dose-dependent effects of caffeine in human Sertoli cells metabolism and oxidative profile: relevance for male fertility. Toxicology. 2015;328:12–20.
12. Reiter LW. Research plan for endocrine disruptors. National Service Center for Environmental Publications; 1998. http://nepis.epa.gov/Exe/ZyPURL. cgi?Dockey=10003A5G.TXT.
13. Bila DM, Dezotti M. Desreguladores endócrinos no meio ambiente: efeitos e consequências. Quim Nova. 2007;30:651–66.
14. Guide for the care and use of laboratory animals, 8th ed. Washington: National Academic Press; 2011. https://grants.nih.gov/grants/olaw/guide-for- the-care-and-use-of-laboratory-animals.pdf.
15. Pachaly JR, Fernando H, de Brito V. Interspecific allometric scaling. In: Sons JW, editor. Biology, medicine, and surgery of South American wild animals. Iowa State University Press: Wiley; 2008. p. 475–81.
16. Oshio LT, Guerra MO. Methods in toxicology of the male reproductive system and fertility in rodents. Interdisciplinary J Exp Stud. 2009;1(3):148–52.
17. Berkey CS, Rockett HR, Field AE, Gillman MW, Colditz GA. Sugar-added beverages and adolescent weight change. Obes Res. 2004;12(5):778–88.
18. Nawrot P, Jordan S, Eastwood J, Rotstein J, Hugenholtz A, Feeley M. Effects of caffeine on human health. Food Addit Contam. 2003;20(1):1–30.
19. Алимова, Н. П., & Асадова, Н. Х. (2020). Изучение анатомии через проблемное обучение среди студентов медиков. In Сборник материалов международной учебной онлайн конференции “Современное состояние медицинского образования: проблемы и перспективы (pp. 138-139).
20. Алимова, Н. П. (2021). Оценка Состояние Детей С Гипертрофий Аденоидов В Педиод Карантина. Барқарорлик ва Етакчи Тадқиқотлар онлайн илмий журнали, 1(6), 774-785.
21. Temirova, N. R. (2022). MORPHOMETRIC INDICATORS OF GROWTH AND DEVELOPMENT OF CHILDREN IN ENDEMIC AREAS. British Medical Journal, 2(1).
22. Safehood: The Food Safety Promotion Board. A review of the health effects of stimulant drinks—final report. In: Food Safety Promotion Board EA, editor. Eastgate, Little Island, Cork; 2002. http://www.safefood.eu/SafeFood/ media/SafeFoodLibrary/Documents/Publications/Research%20Reports/FSPB- Stimulant-drinks.pdf.
23. Kamalova, S. M., & Teshaev, S. J. Comparative Characteristics of Morphometric Parameters of Children with Scoliosis. measurements, 14, 15.
24. Chen W, Guo J, Zhang Y, Zhang J. The beneficial effects of taurine in preventing metabolic syndrome. Food Funct. 2016;7(4):1849–63.
Published
2022-05-21
How to Cite
Muxiddinovna, I. M. (2022). Effects of Energy Drinks on Biochemical and Sperm Parameters in Albino Rats. Central Asian Journal of Medical and Natural Science, 3(3), 126-131. https://doi.org/10.17605/cajmns.v3i3.742
Issue
Section
Articles
