Peculiarities of the Development of Hypothiriosis in Women of the Climacteric Period
Abstract
This article presents the results of a study in which 100 menopausal women were examined. The pituitary-thyroid and pituitary-ovarian status was assessed in groups of women who differed in the functional state of the thyroid gland and in the course of the perimenopausal period. The conducted radioimmunoassay studies made it possible to establish that in the perimenopause there is an aggravation of the functional inferiority of the thyroid gland, especially pronounced in menopausal syndrome (CS), there is a significant mismatch in the activity of the hypothalamic-pituitary structures in CS against the background of hypothyroidism, which, in our opinion, is a predisposing factor to the predominance of severe forms. CS in women with hypothyroidism.
References
2. Bremner AP, Feddema P, Leedman PJ, et al. Age-related changes in thyroid function: a longitudinal study of a community-based cohort. J Clin Endocrinol Metab. 2012;97:1554–1562.
3. Biondi B, Bartalena L, Cooper DS, et al. The 2015 European Thyroid Association guidelines on diagnosis and treatment of endogenous subclinical hyperthyroidism. EurThyroid J. 2015;4:149–163
4. Rodondi N, den Elzen WP, Bauer DC, et al. Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA. 2010;304:1365–1374
5. Russian Congress on Gynecological Endocrinology and Menopause: Scientific program and abstracts. -Yaroslavl, 2004. -S. 85-86.
6. Smetnik V.P. Guide to climacteria, Moskava/2001-685
7. Izmozherova N.V., Popov A.A., Stryukova O.Yu., Andreev A.I., Tagiltseva N.V. Frequency of thyroid dysfunction and cardiovascular pathology in menopausal women. Problems of Endocrinology. 2007;53(1):36-40
