Microwave Assisted Solvent Extraction Study of Ficus Exasperata (Vahl) Stem Bark Antimicrobial Potential Agaisnt Methicillin

  • Ibrahim Jimoh Department of Pure and Industrial Chemistry, Faculty of Physical Sciences, College of Natural and Pharmaceutical Sciences, Bayero University Kano, P.M.B. 3011, Kano State, Nigeria.
  • Usman M. T Department of Physical Sciences, School of Technology, Kano State Polytechnic, Kano, Nigeria.
  • Sulle M. O Department of Biological Science, Confluence University of Science and Technology, Osara, KM 19 Okene-Lokoja road P.M.B 1049 Kogi State, Nigeria
Keywords: Antimicrobial evaluation, Ficus exasperata, Minimum Inhibition Concentration, Microwave, Phytochemical screening

Abstract

Stem bark of Ficus exasperata was extracted using ethyl acetate by microwave-assisted solvent extraction. Phytochemical screening and antimicrobial evaluation were carried out on the extract. Phytochemical screening revealed the presence of cardiac glycosides, tannins, flavonoids, triterpenes and steroids. Antimicrobial evaluation revealed that the extract is active against Methicillin – resistant Staphylococus aureus (MRSA), Staphylococcus aureus, Streptococcus pneumoniae, Salmonella typhi, Proteus mirabilis, Shigella dysenteriea, Candida stellatoidea and Candida tropicalis. The zones of inhibition (mm) for the test organisms were 27, 30, 31, 26, 27, 29, 27and 24 respectively. Minimum inhibition concentrations (mg/L) of extract against  Methicillin – resistant Staphylococus aureus (MRSA), Staphylococcus aureus, Streptococcus pneumonia, Salmonella typhi , Proteus mirabilis, Shigella dysenteriea, Candida stellatoidea and Candida tropicalis were  2.5, 1.25, 1.25, 2.5, 1.25, 1.25, 1.25 and 2.5 respectively. Minimum bactericidal/fungicidal concentrations (mg/L) of extract against Methicillin – resistant Staphylococus aureus (MRSA), Staphylococcus aureus, Streptococcus pneumonia, Salmonella typhi , Proteus mirabilis Shigella dysenteriea Candida stellatoidea and Candida tropicalis were 5,2.5,2.5,5,5,2.5,2.5 and 5 respectively.

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Published
2021-11-23
How to Cite
Jimoh, I., T, U. M., & O, S. M. (2021). Microwave Assisted Solvent Extraction Study of Ficus Exasperata (Vahl) Stem Bark Antimicrobial Potential Agaisnt Methicillin. Central Asian Journal of Medical and Natural Science, 2(6), 117-124. https://doi.org/10.17605/cajmns.v2i6.493
Section
Articles