Evaluation of Some Interleukins In Iraqi Patients With Giardia Infection

Worood Younis  Azawi; Ezz El-Din  Thabet Mahdi; Imad Ahmed  Rashid

doi:10.17605/cajmns.v6i3.2827

Worood Younis Azawi Balad Technical Institute, Middle Technical University
Ezz El-Din Thabet Mahdi College of Medicine, Tikrit University
Imad Ahmed Rashid Balad Technical Institute, Middle Technical University

DOI: https://doi.org/10.17605/cajmns.v6i3.2827

Keywords: giardia lamblia, IL-13, IL-5, IFN-ƴ, giardiasis

Abstract

The purpose of the current investigation is to ascertain how cellular responses contribute to reducing intestine invasion by Giardia. The study team was made up of 40 females and 20 males, aged 16–70, infected with Giardia intestinalis. Laboratory tests (colonoscopy, stool examination) were used to make the diagnosis. Blood was obtained for analysis both before and two weeks following the conclusion of antiparasitic therapy. There were twenty men and twenty-two women in the control group, aged 18 to 55 years. Serum concentrations of IL-5, IL-13, and IFN-ƴ. were measured using Quantikine human assays. Individuals infected with Giardia intestinalis exhibited a statistically significant elevation in IL-13 and IFN-ƴ levels. The levels of these indicators were not lowered by the antiparasitic medication that was supplied.

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