Clinical Manifestation and Immunological Assays for H.Pylori Diagnosis
Abstract
Date palm (Phoenix dactylifera L.) cultivation is a cornerstone of agriculture in arid and semi-arid regions, with significant cultural and economic importance. Specific Background: In Iraq, the date palm sector faces critical challenges due to traditional propagation methods and limited genetic diversity. Despite the known advantages of tissue culture for mass propagation and disease-free plant production, there is insufficient localized research on its effective implementation in Iraqi varieties. This study aimed to evaluate the role of tissue culture technology in the rapid propagation of elite date palm cultivars and its potential to support the recovery of Iraq’s date palm sector. The research demonstrated that tissue culture techniques, specifically somatic embryogenesis and organogenesis, can produce uniform and healthy date palm plantlets, ensuring high propagation rates and genetic fidelity. Additionally, successful acclimatization rates were achieved, indicating the viability of large-scale production. This work provides the first systematic evaluation of tissue culture application for Iraqi date palm cultivars, addressing technical and operational constraints in local laboratories. The findings highlight the potential of biotechnology to revolutionize date palm propagation in Iraq, offering a sustainable solution for germplasm conservation, cultivar improvement, and re-establishment of Iraq’s leadership in date production.
References
S. E. Crowe, "Helicobacter pylori infection," New England Journal of Medicine, vol.380, no.12, pp.1158-1165, 2019.
A. Lee, "Therapeutic immunization against Helicobacter infection," Gastroenterology,vol.110,no.6,pp.2003-2005,1996.
Salillas and J. Sancho, “Flavodoxins as novel therapeutic targets against Helicobacter pylori and other gastric pathogens,” Int. J. Mol. Sci., vol. 21, no. 5, pp. 1881, 2020.
Granstrom, P. Lehours, C. Bengtsson, and F. Mégraud, “Diagnosis of Helicobacter pylori,” Helicobacter, vol. 13, pp. 7–12, 2008.
Schubert, A. B. Schubert, and C. K. Ma, “Symptoms, gastritis, and Helicobacter pylori in patients referred for endoscopy,” Gastrointest. Endosc., vol. 38, no. 3, pp. 357–360, 1992.
Ozbey and A. Hanafiah, “Epidemiology, diagnosis, and risk factors of Helicobacter pylori infection in children,” Euroasian J. Hepato-Gastroenterology, vol. 7, no. 1, pp. 34, 2017.
Wang et al., “Diagnosis of Helicobacter pylori infection: Current options and developments,” World J. Gastroenterol. WJG, vol. 21, no. 40, pp. 11221, 2015.
Dore and G. M. Pes, “What is new in Helicobacter pylori diagnosis. An overview,” J. Clin. Med., vol. 10, no. 10, p. 2091, 2021.
Marshall, B. J., et al. "Urea breath test for diagnosis of Helicobacter pylori infection." The Lancet, vol. 331, no. 8590, pp. 1369-1371, 1988.
Graham, D. Y., et al. "Urea breath test for Helicobacter pylori: a review." Helicobacter, vol. 10, no. 4, pp. 273-283, 2005.
Luck, J. M. "The estimation of urea in the stomach." The Biochemical Journal, vol. 17, no. 4-5, pp. 461-466, 1923.
Graham, D. Y., et al. "Urea breath test for Helicobacter pylori: a review." Helicobacter, vol. 10, no. 4, pp. 273-283, 2005.
Logan, R. P., et al. "Urea breath test for diagnosis of Helicobacter pylori infection." Gut, vol. 32, no. 10, pp. 1141-1143, 1991.
Klein, P. D., et al. "A rapid, non-invasive, reliable method for detecting Helicobacter pylori infection." Gastroenterology, vol. 98, no. 5, pp. A69, 1990.
Epplein, M., et al. "Urea breath test for detection of Helicobacter pylori infection." Journal of Clinical Microbiology, vol. 47, no. 6, pp. 1775-1782, 2009.
Copyright (c) 2025 Nadhim N. Tahir, Ali Naeem Tahir, Ahmed Ali Hussein, Hala Atiyah Ghayad, Eman Karim Mutir, Batool Saleh Chuaied, Hind Ahmed Abd

This work is licensed under a Creative Commons Attribution 4.0 International License.