Pulmonary Tuberculosis is A Clinical Course of The Disease in The Identified Pregnancy

Abstract

Pulmonary tuberculosis remains a significant global public health challenge, with growing prevalence among pregnant women, leading to increased concerns in obstetrics and infectious disease fields. In Uzbekistan, the incidence of tuberculosis in children has increased by 2.4 times over the past two decades, while pregnancy complicates the clinical management due to immunological changes and fetal vulnerability. Despite the known risks, limited data exist on the clinical presentation and outcomes of pulmonary tuberculosis during pregnancy in regional contexts. This study aimed to evaluate the clinical course of pulmonary tuberculosis in pregnant women and assess associated complications. A retrospective analysis of 9 pregnant women revealed that 66.6% had unilateral lung involvement, 33.3% had infiltrative forms, and 88.8% had detectable Koch’s bacilli. Anemia was present in all patients, with 23% experiencing severe anemia. Cesarean section was required in four cases, and one pregnancy was terminated due to uterine bleeding. The study provides region-specific clinical insights into the manifestation of tuberculosis during pregnancy and its management under the DOTS program. Early detection, careful radiological evaluation, and timely obstetric intervention, including cesarean delivery, can significantly improve maternal and neonatal outcomes. The findings underscore the need for integrated approaches in managing tuberculosis in pregnancy, particularly in high-burden regions.