Optimization of Treatment For Sensorineural Hearing Loss of Infectious Origin

Kh.E Karabaev; Karimova  M. M

doi:10.17605/cajmns.v6i4.2748

Kh.E Karabaev Tashkent Pediatric Medical Institute, Tashkent, st. Bogishamol 223, 100140, Uzbekistan, tel: + 998 99 8070600,
Karimova M. M Samarkand State Medical University, Samarkand, 140100, Uzbekistan

DOI: https://doi.org/10.17605/cajmns.v6i4.2748

Keywords: Sensorineural hearing loss, cytomegalovirus, toxoplasmosis, pediatric audiology, antiviral therapy, immunocorrection, auditory brainstem response, cytokine correlation.

Abstract

The aim of this work was to optimize treatment methods for sensorineural hearing loss of infectious genesis. The object of the study was 115 children in the age category from 1 year to 7 years with SNHL in association with toxoplasmosis and CMV infection, who were included in the main group and in the comparative group of 30 children diagnosed with SNHL without toxoplasmosis and CMV infection. The main group received antiviral therapy, and the comparison group received traditional therapy. Both study groups underwent whispered and spoken speech perception tests. Hearing Improvement Based on Speech Perception Tests. Whispered speech perception test (up to 3 meters): Before treatment, 6 children (5.2%) in the main group were diagnosed with Grade I SNHL. Spoken speech perception test (up to 6 meters): Before treatment, 7 children (6.1%) in the main group were diagnosed with SNHL. To achieve the set goals, the authors also conducted ABR after treatment in the study groups. Thus, strong correlation relationships were revealed between specific antibodies of pathogens, cytokine status, and inflammatory proteins.

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