The Impact of Trace Elements and Lipid Levels on Blood Pressure: A Clinical Biochemistry Study
Abstract
Trace elements and lipid levels play a crucial role in blood pressure regulation, influencing vascular function and potentially contributing to hypertension. Investigate the relationship between trace elements and lipid levels and their impact on blood pressure regulation, with a focus on understanding their potential role in the development of hypertension. This case-control study, conducted from August 1 to November 1, 2024, at Al-Habboubi Teaching Hospital with ethical approval, involved blood sample collection under aseptic conditions. Plasma and serum were separated by centrifugation and stored at -20°C. Trace elements (zinc, copper, and selenium) were measured using Atomic Absorption Spectrometry (AAS), and lipid profile parameters (total cholesterol, LDL, HDL, and triglycerides) were analyzed with a spectrophotometer. The results showed that the gender distribution between the hypertensive and control groups was balanced, with similar mean ages. The proportion of individuals with secondary education was higher in the hypertensive group, while marital status showed a higher proportion of married individuals in the hypertensive group. Significant increases in systolic and diastolic blood pressure, heart rate, total cholesterol, LDL, and triglycerides were observed in the hypertensive group compared to the control group. Zinc levels were lower in the hypertensive group, while copper and selenium were also lower, but the differences were not statistically significant. HDL levels were lower in the hypertensive group. The study found that high blood pressure is linked to big changes in lipid profile, heart rate, and blood pressure. Some of these changes are higher levels of HDL and lower levels of total cholesterol, LDL, and lipids. This means that trace elements may have something to do with high blood pressure. Zinc, copper, and selenium were found in smaller amounts.
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