Evaluation of Hair Loss and Some Physiological Factors in Female’s Patients Attended Dermatological Clinics at Ramadi General Hospital
Keywords:
Hair loss, Thyroid gland hormones, Vitamins, Zinc, Ferritin, Iron
Abstract
Hair loss is a difficult problem that is common to many 'dermatologists'. It is also considered an annoying trouble for females due to the relationship between hair within femininity, beauty and individual strength, and therefore it may cause psychicl trouble for them. especially in the city of Ramadi (Western Iraq), (, there was little attention to it. The study aimed to Validating role of the main physiological of the common causes of hair loss. The study was conducted during the period from March to September, 2022. This study was applied on 80 volunteer women who visited the dermatology clinics in general Ramadi hospital. The blood sample was collected from the patient group (A total of 52 volunteer women with suffering hair loss), along with the control group (28 healthy women) for the purpose of comparison. Serum T3, T4, TSH, Vit D3 and Ferritin level measured by using the Cobase 411(Roche) full –automated mechanics. The result showed 'a significantly lower' level in the concentration of vitamin D3, vitamin B12 and serum ferritin and a significant higher mean in serum concentration of T3 hormone in the group of patients. Additionally, the results exhibited non a significantly different in age, Hb, T4 and TSH of patient group compared to the control group. This study demonstrated the importance of physiological factors might play a major role in the etiology of hair loss between women in the city of Ramadi.
References
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Rajput R (2017) Role of non-androgenic factors in hair loss and hair regrowth. J Cosmo Trichol. 3(2), 118.
Kareem JB, Yser HT, Abou Turab MK and Makki UM (2020) Effect of malnutrition, hormones disturbance and malondialdehyde on hair loss in women: patients at ALSADER educational hospital, Basrah Governorate, Iraq - A case study. Biochem. Cell. Arch.;20(2), pp. 5701-5708
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Harrison S and Sinclair R (2002) Telogen effluvium. Clinical and Experimental Dermatology: Clinical dermatology 27(5), 389- 395
Garg S, Mishra S, Tondon R, and Tripathi K (2012) Hodgkin's Lymphoma Presenting as Alopecia; Int J Trichology. Jul-Sep; 4(3): 169–171 doi: 10.4103/0974-7753.100085.
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Bikle D D, Oda Y, Tu C L and Jiang Y (2015) Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer. The J. Steroid Biochem. Mole. Biol. 148, 47-51
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Turkan TA and Al-Rawi JR (2021) Vitamin D level and telogen hair loss: A Case control study: J Fac Med Baghdad; 63 (3):117-122
Rasheed H, Mahgoub D, Hegazy R, El-Komy M, Abdel Hay R, Hamid MA, Hamdy E (2013) Serum ferritin and vitamin d in female hair loss: do they play a role? Skin Pharmacol Physiol. 26(2):101-7. doi: 10.1159/000346698. Epub 2013 Feb 20. PMID: 23428658
Roem NR, Tarib F, NN, Wasodo, Patellongi I, Bukhair A, Nafie NL (2016) Hair’s zinc level on androgenic alopecia. Am J of Clin and Exp Med.;4(5):129-33
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Rebora A (2019) Telogen effluvium: A comprehensive review. Clin Cosmet Investig Dermatol. 12: 583.
Mazhar MW (2021) (Thyroidism Effect on Alopecia Patients in Pakistan. Sys Rev Pharm. 12(12): 3907-3908
Trost LB, Bergfeld WF, Calogeras E (2005) The diagnosis and treatment of iron deficiency and its potential relationship to hair loss. J Am Acad Dermatol. 2006 May;54(5):824-44. doi: 10.1016/j.jaad. 11.1104.PMID: 16635664
Ozuguz. Pinar, Kacar Seval Dogruk, E. Ozlem, Karaca Semsettin (2015) Evaluation of Zinc, Vitamin B12, Folic Acid and Iron Levels and Thyroid Functions in Patients
with Chronic Telogen Effluvium. JDRT-1-008. DOI: 10.23937/2469-5750/1510008
Coad J and Conlon C (2011) Iron deficiency in women: assessment, causes and consequences. Curr Opin Clin Nutr Metab Care; 14:625–634.
Dinh QQ, Sinclair R (2007) Female pattern hair loss: current treatment concepts. Clinical Interventions in Aging; 2:189-99.
Almohanna H M, Ahmed A A, Tsatalis J P and Tosti A (2019) The role of vitamins and minerals in hair loss: a review. Dermatology and Therapy 9(1), 51-70
Abdel Fattah N S, Atef M M, Al‐Qaradaghi SM, (2016). Evaluation of serum zinc level in patients with newly diagnosed and resistant alopecia areata. International journal of dermatology, 55(1), 24-29
Rockville M (2014) Understanding the Impact of TraumaChapter 3, Trauma-Informed Care in Behavioral Health Services. Treatment Improvement Protocol (TIP). Series, No. 57. Center for Substance Abuse Treatment (US). Substance Abuse and Mental Health Services Administration (US); Report No.: (SMA) 14-4816.
Maraee AH, El-EsrigyFA, Elsayed HM. Telogen Effluvium (2018) Prevalence Associated Factors with Reference to Iron Deficiency Anemia among Childbearing Women, Gharbia Governorate, Egypt. Egyptian Family Medicine Journal; 2(1):33-44.
Elledge S J, Zhou Z and Allen J B (1992) Ribonucleotide reductase: regulation, regulation, regulation. Trends in Biochemical Sciences 17(3), 119-123.
Saini K and Mysore V (2021) Role of vitamin D in hair loss: A short review. J Cosmet Dermatol. Nov;20(11):3407-3414. doi: 10.1111/jocd.14421. Epub 2021 Sep 22. PMID: 34553483 Review.
Turkan TA. And Al-Rawi JR (2021) Vitamin D level and telogen hair loss: A Case control study. J Fac Med Baghdad; Vol. (63), No. (3):117-122. DOI: https://doi.org/10.32007/jfacmedbagdad.6331846
Mustafa AJ, Balaky HM, Ismail PA (2023) The role of Adipocytokines, Vitamin D, and C in Colorectal Cancer. Baghdad Sci.J: 16:20(3):0690
Ertug E Y and Yilmaz R A (2018) Reduced ferritin, folate, and vitamin B12 levels in female patients diagnosed with telogen effluvium. Int J Med Biochem;1(3):111-4. DOI: 10.14744/ijmb.2018.75047.
Archana Shetty and Vijaya (2019) A study of hematological parameters and their correlation with thyroid hormone status in non-pregnant women of childbearing age. Indian J. Pathol. Oncol. 6(1), 102-106.
Brakhas SA, Rahmah AM, Jassim AN (2012) Evaluation the Levels of Serum Hormones (Progesterone, Estradiol, and hCG) in Preeclamptic IraqiPregnancies. Baghdad Sci.J.: 9(2):244-50.
Alwan IF, Mohammed HA, Hmood A (2014) Preparation and diagnostic medicinal substance for regulating the thyroid gland. Baghdad Sci.J;11(2):342-9.
Rajput R (2017) Role of non-androgenic factors in hair loss and hair regrowth. J Cosmo Trichol. 3(2), 118.
Kareem JB, Yser HT, Abou Turab MK and Makki UM (2020) Effect of malnutrition, hormones disturbance and malondialdehyde on hair loss in women: patients at ALSADER educational hospital, Basrah Governorate, Iraq - A case study. Biochem. Cell. Arch.;20(2), pp. 5701-5708
Naif AA (2016) Telogen Effluvium: Potential causes in Iraq. Thi-Qar Medical J. 12(2), 112-120.
Harrison S and Sinclair R (2002) Telogen effluvium. Clinical and Experimental Dermatology: Clinical dermatology 27(5), 389- 395
Garg S, Mishra S, Tondon R, and Tripathi K (2012) Hodgkin's Lymphoma Presenting as Alopecia; Int J Trichology. Jul-Sep; 4(3): 169–171 doi: 10.4103/0974-7753.100085.
Finner AM (2013) Nutrition and hair: deficiencies and supplements. Dermatologic Clinics;31(1): 167–172.
Ross AC, Taylor CL, Yaktine AL, and Del Valle HB (2011) Dietary Reference Intakes for Calcium and Vitamin D. Washington (DC): National Academies Press (US); PMID: 21796828 Bookshelf ID: NBK56070 DOI: 10.17226/13050
Nayak K, Garg A, Mithra P, Manjrekar P (2016) Serum Vitamin D 3 Levels and Diffuse Hair Fall among the Student Population in South India: A Case-Control Study. Int J Trichology. Oct-Dec;8(4):160-164. doi: 10.4103/ijt.ijt_57_16
Demay MB, MacDonald PN, Skorija K, Dowd DR, Cianferotti L, Cox M (2007) Role of the vitamin D receptor in hair follicle biology; J Steroid Biochem Mol Biol. Mar;103(3-5):344-6. doi: 10.1016/j.jsbmb.2006.12.036. Epub Jan 16.
Bikle D D, Oda Y, Tu C L and Jiang Y (2015) Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer. The J. Steroid Biochem. Mole. Biol. 148, 47-51
Dhaher SA and Alwan MH (2020) Role of Vitamin D in Female Pattern Hair Loss Among Iraqi Women: A Case- Control Study: The Medical Journal of Basrah University, Volume 38, Issue 2, Pages 55-64
Turkan TA and Al-Rawi JR (2021) Vitamin D level and telogen hair loss: A Case control study: J Fac Med Baghdad; 63 (3):117-122
Rasheed H, Mahgoub D, Hegazy R, El-Komy M, Abdel Hay R, Hamid MA, Hamdy E (2013) Serum ferritin and vitamin d in female hair loss: do they play a role? Skin Pharmacol Physiol. 26(2):101-7. doi: 10.1159/000346698. Epub 2013 Feb 20. PMID: 23428658
Roem NR, Tarib F, NN, Wasodo, Patellongi I, Bukhair A, Nafie NL (2016) Hair’s zinc level on androgenic alopecia. Am J of Clin and Exp Med.;4(5):129-33
H. Park, C. W. Kim, S. S. Kim, and C. W. Park (2009) The therapeutic effect and the changed serum zinc level after zinc supplementation in alopecia areata patients who had a low serum zinc level”. Annals of Dermatology, vol. 21, no. 2, pp. 142–146
Rebora A (2019) Telogen effluvium: A comprehensive review. Clin Cosmet Investig Dermatol. 12: 583.
Mazhar MW (2021) (Thyroidism Effect on Alopecia Patients in Pakistan. Sys Rev Pharm. 12(12): 3907-3908
Trost LB, Bergfeld WF, Calogeras E (2005) The diagnosis and treatment of iron deficiency and its potential relationship to hair loss. J Am Acad Dermatol. 2006 May;54(5):824-44. doi: 10.1016/j.jaad. 11.1104.PMID: 16635664
Ozuguz. Pinar, Kacar Seval Dogruk, E. Ozlem, Karaca Semsettin (2015) Evaluation of Zinc, Vitamin B12, Folic Acid and Iron Levels and Thyroid Functions in Patients
with Chronic Telogen Effluvium. JDRT-1-008. DOI: 10.23937/2469-5750/1510008
Coad J and Conlon C (2011) Iron deficiency in women: assessment, causes and consequences. Curr Opin Clin Nutr Metab Care; 14:625–634.
Dinh QQ, Sinclair R (2007) Female pattern hair loss: current treatment concepts. Clinical Interventions in Aging; 2:189-99.
Almohanna H M, Ahmed A A, Tsatalis J P and Tosti A (2019) The role of vitamins and minerals in hair loss: a review. Dermatology and Therapy 9(1), 51-70
Abdel Fattah N S, Atef M M, Al‐Qaradaghi SM, (2016). Evaluation of serum zinc level in patients with newly diagnosed and resistant alopecia areata. International journal of dermatology, 55(1), 24-29
Rockville M (2014) Understanding the Impact of TraumaChapter 3, Trauma-Informed Care in Behavioral Health Services. Treatment Improvement Protocol (TIP). Series, No. 57. Center for Substance Abuse Treatment (US). Substance Abuse and Mental Health Services Administration (US); Report No.: (SMA) 14-4816.
Maraee AH, El-EsrigyFA, Elsayed HM. Telogen Effluvium (2018) Prevalence Associated Factors with Reference to Iron Deficiency Anemia among Childbearing Women, Gharbia Governorate, Egypt. Egyptian Family Medicine Journal; 2(1):33-44.
Elledge S J, Zhou Z and Allen J B (1992) Ribonucleotide reductase: regulation, regulation, regulation. Trends in Biochemical Sciences 17(3), 119-123.
Saini K and Mysore V (2021) Role of vitamin D in hair loss: A short review. J Cosmet Dermatol. Nov;20(11):3407-3414. doi: 10.1111/jocd.14421. Epub 2021 Sep 22. PMID: 34553483 Review.
Turkan TA. And Al-Rawi JR (2021) Vitamin D level and telogen hair loss: A Case control study. J Fac Med Baghdad; Vol. (63), No. (3):117-122. DOI: https://doi.org/10.32007/jfacmedbagdad.6331846
Mustafa AJ, Balaky HM, Ismail PA (2023) The role of Adipocytokines, Vitamin D, and C in Colorectal Cancer. Baghdad Sci.J: 16:20(3):0690
Ertug E Y and Yilmaz R A (2018) Reduced ferritin, folate, and vitamin B12 levels in female patients diagnosed with telogen effluvium. Int J Med Biochem;1(3):111-4. DOI: 10.14744/ijmb.2018.75047.
Archana Shetty and Vijaya (2019) A study of hematological parameters and their correlation with thyroid hormone status in non-pregnant women of childbearing age. Indian J. Pathol. Oncol. 6(1), 102-106.
Brakhas SA, Rahmah AM, Jassim AN (2012) Evaluation the Levels of Serum Hormones (Progesterone, Estradiol, and hCG) in Preeclamptic IraqiPregnancies. Baghdad Sci.J.: 9(2):244-50.
Alwan IF, Mohammed HA, Hmood A (2014) Preparation and diagnostic medicinal substance for regulating the thyroid gland. Baghdad Sci.J;11(2):342-9.
Published
2024-09-03
How to Cite
Mustafa, T. I., Mutlak , S. S., Al Hayani, D. A., Awad, N. A., & Noori, S. S. (2024). Evaluation of Hair Loss and Some Physiological Factors in Female’s Patients Attended Dermatological Clinics at Ramadi General Hospital. Central Asian Journal of Medical and Natural Science, 5(4), 711-721. Retrieved from https://cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/2601
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