Relation of some Physiological and Biochemical Parameters with Jaundice in Newborns
Abstract
The current study aimed to know the effect of jaundice in newborns on some physiological and biochemical parameters and compare them with healthy children. The study showed that the incidence rate in male children is greater than female children. As for liver enzymes (ALT) and (ALP), Comparing the results to healthy individuals, it was shown that there was a notable rise in enzyme activity as well as a notable drop in enzyme activity. The study also showed changes in some levels of Glucuronosyl Transferase (GUT1 (oxidative stress MDA) malondialdehyde) and some antioxidants such as (GSH) in the body, where we noticed a decrease in the level of (GSH) compared to healthy people. Thus, we conclude from this current study that jaundice is associated with several factors, including liver metabolism and levels of oxidative stress and the mechanism of bile secretion from the gallbladder.
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