The Effect of Amoebic Dysentery on Some Physiological Parameters
Keywords:
Amoebic Dysentery, Some Physiological Parameters, Iraq
Abstract
The study was conducted in Anbar Governorate on patients visiting Fallujah Women's and Children's Hospital and some private laboratories in Fallujah for age groups ranging from (20-1) years and for both sexes. The collection period lasted from July 2023 to December 2023 and amoebic dysentery was diagnosed through microscopic examination of stool samples to investigate the parasite Entamoeba histolytica, and 30positive samples were recorded out of 120 samples and the infection rate reached 25%. The concentration of SOD, CAT, GSH, MDA, G.H and Ghrelin were studied for infected and healthy individuals. The results of the current study showed highly significant differences for CAT for those infected with amoebic dysentery compared to healthy individuals. As for SOD and MDA, they showed a significant difference for those infected compared to healthy individuals. As for G.H and Ghrelin, they did not show any significant differences for those infected compared to healthy individuals. Highly significant differences were shown for SOD for those infected and for both sexes compared to healthy individuals. As for MDA, they showed a significant difference for those infected compared to healthy individuals. As for CAT, GSH, G.H and Ghrelin, they did not show any significant differences for those infected with E.histolytica and for both sexes compared to healthy individuals.
References
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Petri and Frederick, J.R., W.A.( 2005). Roles for the galactose\n-acetylgalactoseamine binding lectin of Entamoeba in parasite virulence and differentiation. Mol. Biochem. Parasitol.,137: 339-343.
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Schatzman, S. S., Peterson, R. L., Teka, M., He, B., Cabelli, D. E., Cormack, B. P., & Culotta, V. C. (2020). Copper-only superoxide dismutase enzymes and iron starvation stress in Candida fungal pathogens. Journal of Biological Chemistry, 295(2), 570-583 .
Seif, M. A., & Al-Mohammed, H. I. (2021). Assessment of the Oxidative and Nitrosative Stress in the Serum of Saudi Patients with Cutaneous Leishmaniasis Before and After Treatment. The Journal of parasitology, 107(5), 81 .816-0.
Shannon, N.; Moonah, N.; and William, A. (2013). Host Immune response to intestinal amebiasis. PLOS Pathoge. ( 9) :71 – 85.
Sim, S.; Yong, TS.; Park, SJ.; Im, KI.; Kong, Y.; Ryu, JS.; Min, DY. and Shin, MH. (2005) NADPH Oxidase derived reactive oxygen species-mediated activation of ERK1/2 is required for apoptosis ofhuman neutrophils induced by Entamoebahistolytica; J Immunol.; 174(7): 4279-4288.
Singh, A .; Ericttouft, B.H. and William, A.C. (2009 ). Rapid diagnosis of intestinal parasitic protozoa .J. Infect. Dis.,61(3): 280-286 .
Tengku, S.A. and Norhayati, M.(2011). Public health and clinical importance of amoebiasis in Malaysia: A review. Trop Biomed, 28:194–222.
Wesel, J.; Shuman, J.; Bastuzel, I.; Dickerson, J. and Ingram-Smith, C. (2021). Encystation of Entamoeba histolytica in Axenic Culture. Microorganisms, 9(4), 873.
Yazar, S. ; Kilic, E. ; Saraymen, R. and Sahin, I. (2003) Serum malodialdehyde levels in Toxoplasma Seropositive patients.Annals of Saudi Medicine.; 23 :413-415.
Al-Hassani, M. K. K., & Al-Mayali, H. M. H. (2020). Evaluation of some biochemical levels in patients with Cutaneous leishmaniasis serum and their relationship with antioxidant enzymes. EurAsian J Biosci, 14(1), 1999-2006
Al-Warid, H. S., Al-Saqur, I. M., Al-Tuwaijari, S. B., & Zadawi, K. A. A. (2017). The distribution of cutaneous leishmaniasis in Iraq: demographic and climate aspects. Asian Biomedicine, 11(3), 255- 260 .
Brooks , G. F., Butel, J. S., and Morse , S.A.(2004). Medical Microbiology. MacGraw – Hill companies. Inc. U.S.A. 23rd Ed. PP; 671-674.
Brown , M.S. , & Goldstein ,J .L.(1983). Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis .Anmal review of biochemistry , 52(1), 223-261.
Chen, H.; George, P.; Eric, L.; Schneider, I.; Kerr,E.;Ken, H.;David, G.;Mohammed, S.;Sarah, E.; Boyd, P.; Hruz,E.; Christine, L.;,Wei-ting, L.;Lars, E.; Pieter, C.; Dorrestein,
E.;R. and Sharon, L.(2010). A novel Entamoeba histolytica cysteine Proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target. J Bio. Chi, 285: ( 24) 18516–1527.
Davhana NC, ElBakri AK, Bessong PO, Samie A. (2020) . Association of genetic polymorphism at tumor necrosis factor-α gene promoter - 1031T/C and parasitic infections among children in Northern South Africa. Heliyon. 6(10):e05129.
Demirci, M, ; Delibas, N.; Altuntas, I.; Oktem, F. and Yönden Z. (2003) Serum iron, zinc and copper levels and lipid peroxidation in children with chronic giardiasis; J health popular Nutr.; 21(1): 72-75.
Fotedar, R.; Stark, D.; Beebe, N.; Marriott, D., Ellis, J. and Harkness, J.( 2007). Laboratory diagnosis techniques for Entamoeba histolytica. J. Clin. Microbiol. Rev., 20(3): 511-532.
Ghasemi, E, Rahdar, M and Rostami, M (2015). Prevalence of Entamoeba histolytica/dispar in drinking water in the city of Shush, Khuzestan Province in 2011. Int J Curr Microbiol App Sci. 4, pp. 582–588.
Gopal, N.; Selvam, A.; Srinivasan, A. R.; Saha S.; and Muddegowda, P. H. (2012). Serum Gamma Glutamyl Transferase levels in Obese South Indian adults with reference to atherogenic lipid risk factors and lipid peroxides. Inter. J. Med. Health Sci. 1(1):2- 14.
Ismail S Al-KakeyRafidain.(2006).Lipid Peroxidation and some Haematological Changes in Entamoeba histolytica patients. Journal of Science 17 (9), 10-16.
Kadir, M. A., El-Yassin, S. T., and Ali, A. M. (2018). Detection of Entamoeba histolytica and Giardia lamblia in children with diarrhea in Tikrit city. Tikrit J Pur Sci, 23(6): 57-64.
Kaya S.; Sutcu R.; Cetin E S.; Arıdogan B C.;Delibas N.; and Demirci M.(2007) Lipid peroxidation level and antioxidant enzyme activities in the blood of patients with acute and chronic fascioliasis. International Journal of Infectious Diseases.; 11, 251—255.
Khan,R.; Hamid,S.and Abid,S.(2008)"Predictive factors for early aspiration in liver abscess" world journal of Gastroenterology,14(13):2089-2093.
Kurt,O.;Demirel,M.;Ostan,I.;Sevil,N.R.;Mandiracioglu,A.;Tanyuksel,M.;Ak,M. and Dagci,H. (2008). Investigation of the prevalence of amoebiasis in Izmir province and determination of Entamoeba spp using PCR and enzyme immunoassay. New Microbiol. 31: 393-400.
Madhikarmi, N. L., & Murthy, K. R. S. (2011). Effect of iron deficiency anemia on lipid peroxidation and antioxidant systems. Journal of College of Medical Sciences-Nepal, 7(4), 34-43.
MahmoodAdnanAzawy.(2021)Epidemiological study of Entamoeba histolytica among children in Kirkuk Province, Iraq. Annals of the Romanian Society for Cell Biology 25 (7), 1915-1925.
Mercedes Gil-Campos, Concepción María Aguilera, Ramón Canete, Angel Gil.(2006). Ghrelin: a hormone regulating food intake and energy homeostasis. GilBritish Journal of Nutrition 96 (2), 201-226.
Morgan, T.M. and Case, L.D. (2013). Conservative samle size determination for repeated measures analysis of covariance, Ann Biom Biostate, 1(1). Jingeez AHameed, Omaima .
Nandi, A.; Yan, L. J.; Jana, C. K. and Das, N. (2019). Role of catalase in oxidative stress-and age-associated degenerative diseases. Oxidative medicine and cellular longevity, 2019.of Disease. Infect. Immun.,71(9):5355-5359.
Nazli Khatib, Shilpa Gaidhane, Abhay M Gaidhane, Mahanaaz Khatib, Padam Simkhada, Dilip Gode, Quazi Syed Zahiruddin.(2014). Ghrelin: ghrelin as a regulatory Peptide in growth hormone secretion. "Journal of clinical and diagnostic research: JCDR 8 (8), MC13.
Patricia Mora Criollo, Retoprata Basso Ya Nrong Qian Jaime A. Costales Jaime Guevara Aguirre, Mario G. Greg Alva, John G. Kupchik.(2022).Growth hormone regulates Trypanosoma cruzi infection in vitro.Growth Hormone Research IGF64,101,460.
Petri and Frederick, J.R., W.A.( 2005). Roles for the galactose\n-acetylgalactoseamine binding lectin of Entamoeba in parasite virulence and differentiation. Mol. Biochem. Parasitol.,137: 339-343.
Pour-Aboughadareh, A.; Omidi, M.; Naghavi, M.R.; Etminan, A.; Mehrabi, A.A.; and Poczai, P. (2020) Wild Relatives of Wheat Respond Well to Water Deficit Stress: A Comparative Study of Antioxidant Enzyme Activities and Their Encoding Gene Expression. Agriculture, 10, 415.
Powers M (2005). "Performance-Enhancing Drugs". في Deidre Leaver-Dunn; Joel Houglum; Harrelson, Gary L. (المحرر). Principles of Pharmacology for Athletic Trainers. Slack Incorporated. ص. 331–332 .
Schatzman, S. S., Peterson, R. L., Teka, M., He, B., Cabelli, D. E., Cormack, B. P., & Culotta, V. C. (2020). Copper-only superoxide dismutase enzymes and iron starvation stress in Candida fungal pathogens. Journal of Biological Chemistry, 295(2), 570-583 .
Seif, M. A., & Al-Mohammed, H. I. (2021). Assessment of the Oxidative and Nitrosative Stress in the Serum of Saudi Patients with Cutaneous Leishmaniasis Before and After Treatment. The Journal of parasitology, 107(5), 81 .816-0.
Shannon, N.; Moonah, N.; and William, A. (2013). Host Immune response to intestinal amebiasis. PLOS Pathoge. ( 9) :71 – 85.
Sim, S.; Yong, TS.; Park, SJ.; Im, KI.; Kong, Y.; Ryu, JS.; Min, DY. and Shin, MH. (2005) NADPH Oxidase derived reactive oxygen species-mediated activation of ERK1/2 is required for apoptosis ofhuman neutrophils induced by Entamoebahistolytica; J Immunol.; 174(7): 4279-4288.
Singh, A .; Ericttouft, B.H. and William, A.C. (2009 ). Rapid diagnosis of intestinal parasitic protozoa .J. Infect. Dis.,61(3): 280-286 .
Tengku, S.A. and Norhayati, M.(2011). Public health and clinical importance of amoebiasis in Malaysia: A review. Trop Biomed, 28:194–222.
Wesel, J.; Shuman, J.; Bastuzel, I.; Dickerson, J. and Ingram-Smith, C. (2021). Encystation of Entamoeba histolytica in Axenic Culture. Microorganisms, 9(4), 873.
Yazar, S. ; Kilic, E. ; Saraymen, R. and Sahin, I. (2003) Serum malodialdehyde levels in Toxoplasma Seropositive patients.Annals of Saudi Medicine.; 23 :413-415.
Published
2024-07-30
How to Cite
Abdullah, J. S., & Zangana, A. J. M. (2024). The Effect of Amoebic Dysentery on Some Physiological Parameters. Central Asian Journal of Medical and Natural Science, 5(4), 359-366. Retrieved from https://cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/2558
Section
Articles
