Relationship Between Health-Related Quality of Life and Sociodemographic Characteristics Among Women with Polycystic Ovarian Syndrome
Abstract
This study aims to determine the relationship between health-related quality of life (HRQoL) in women with polycystic ovary syndrome (PCOS) and their sociodemographic characteristics. A descriptive correlational design was used for this study, conducted from December 2023 to May 2024. A non-probability (convenience sampling) sample of 400 women was selected from infertility clinics in Babylon City, Iraq. Data were collected using a questionnaire that included sociodemographic characteristics and the PCOS-related HRQoL scale. Data analysis was performed using the SPSS software version 27, applying non-parametric statistical tests such as Spearman's correlation, Mann-Whitney U test, and Kruskal-Wallis test. The results showed that the average age of the participants was 28.95 years, with an average marriage duration of 7.43 years. There were significant correlations between HRQoL dimensions and women's sociodemographic characteristics. Specifically, the study found a positive relationship between body mass index (BMI) and HRQoL, while there was a negative relationship between the number of children and HRQoL. Women with more children tended to have better PCOS-related quality of life in terms of physical symptoms. In contrast, women without children or with fewer children experienced worse quality of life related to infertility, acne, and overall HRQoL. The study indicates that the fewer children women with PCOS have, the poorer their health-related quality of life is in terms of infertility, acne, and overall HRQoL. Conversely, the more children they have, the better their quality of life is in terms of physical symptoms. Additionally, there is a relationship between BMI and HRQoL in women with PCOS, with higher BMI being associated with better HRQoL in terms of weight, physical symptoms, and overall scale.
References
2. Abdullah B, Abdulwahid H. Reproductive-Related Factors Influencing Pregnant Women Satisfaction Towards Vaccination Services. Journal of Obstetrics, Gynecology and Cancer Research. 2023;8(4):408–14.
3. Abed R. Quality of Life of Asthmatics Patients at Baghdad Teaching Hospitals. Kufa Journal for Nursing Sciences. 2016;6(2):26–34.
4. Alabedi G, Naji A. Impact of physical activity program upon elderly quality of life at Al-Amara city/Iraq. Medico-Legal Update. 2020;20(3):544–9.
5. Alabedi G, Naji A. Impact of Physical Activity Program upon Elderly Quality of Life at Al-Amara City/Iraq. Medico-Legal Update [Internet]. 2020 Jul 12;20(3):1223–8. Available from: http://ijop.net/index.php/mlu/article/view/1567
6. Alowairdhi Y, Alrasheed F, Alghubaywi F, Alqirnas MQ, Alajroush WA. Association between acne vulgaris and body mass index in adult population: A tertiary hospital-based retrospective study in Riyadh, Saudi Arabia. Cureus (Internet). 2022 Dec 23 (cited 2024 Jun 17);14(12):e32867.
7. Azziz R. How polycystic ovary syndrome came into its own. F&S Science. 2021 Feb;2(1):2–10.
8. Baker F, Abdulwahid H. Impact of danger signs during pregnancy upon pregnancy outcomes among pregnant women in Al-Diwania city. Indian Journal of Public Health Research and Development. 2019;10(10):2865–9.
9. Bazarganipour F, Ziaei S, Montazeri A, Foroozanfard F, Faghihzadeh S. Health-re1ated quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome. Iranian Journal of Reproductive Medicine (Internet). 2013 May (cited 2024 Jun 17);11(5):371–8.
10. Coffey S, Mason H. The effect of polycystic ovary syndrome on health-related quality of life. Gynecological Endocrinology. 2003 Jan;17(5):379–86.50. Rosenfield RL, Ehrmann DA. The pathogenesis of polycystic ovary syndrome (PCOS): The hypothesis of PCOS as functional ovarian hyperandrogenism revisited. Endocrine Reviews [Internet]. 2016 Jul 26;37(5):467–520. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045492/table/T1/?report=objectonly
11. Diamanti-Kandarakis E. Polycystic ovarian syndrome: pathophysiology, molecular aspects and clinical implications. Expert Reviews in Molecular Medicine. 2008 Jan 30;10.
12. Fauser BCJM, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, et al. Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. Fertility and Sterility [Internet]. 2012 Jan;97(1):28-38.e25. Available from: https://www.asrm.org/globalassets/asrm/asrm-content/news-and-publications/practice-guidelines/for-non-members/consensusonwomenshealthaspectsofpcos-pdfnoprint.pdf
13. Genazzani AR, IbáñezL, Milewicz A, Shah D. Frontiers in gynecological endocrinology. Volume 8, Impact of polycystic ovary, metabolic syndrome and obesity on women health. Cham: Springer; 2021.
14. Hakman EY, Naji AB. Treatment Adherence and its Quality of Life among Patients with Type II Diabetes Mellitus. History of Medicine. 2023;9(2):351–5
15. Ilie IR, Georgescu CE. Polycystic Ovary Syndrome-Epigenetic Mechanisms and Aberrant MicroRNA. Advances in Clinical Chemistry [Internet]. 2015;71:25–45. Available from: https://pubmed.ncbi.nlm.nih.gov/26411410/
16. Isam S, Hassan H. Effect of six-minute walk test on health-related quality of life in patients undergoing coronary artery bypass graft surgery. Rawal Medical Journal. 2023;48(3):655–8.
17. Jones GL. The Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (PCOSQ): A validation. Human Reproduction. 2004 Feb 1;19(2):371–7.
18. Khshain W, Abdulwahid H. Evaluation of Pregnant Women Health Promotive Behaviors Related to Perceived Severity. Bahrain Medical Bulletin. 2023;45(3):1618–23.
19. Kokosar M, Benrick A, Perfilyev A, Fornes R, Nilsson E, Maliqueo M, et al. Epigenetic and transcriptional alterations in human adipose tissue of polycystic ovary syndrome. Scientific Reports. 2016 Mar 15;6(1).
20. Ligocka N, Karolina Chmaj-Wierzchowska, Katarzyna Wszołek, Wilczak M, Tomczyk K. Quality of Life of Women with Polycystic Ovary Syndrome. Medicina-lithuania. 2024 Feb 9;60(2):294–4.
21. Ricci S, Kyle T, Carman S. Maternity and Pediatric Nursing. Lippincott Williams & Wilkins; 2020.
22. Sas K, Reich A. High Body Mass Index is a Risk Factor for Acne Severity in Adolescents: A Preliminary Report. Acta dermatovenerologica Croatica: ADC (Internet). 2019. 27(2):81–5.
23. Shamkh S, Nagi A. Impact Of Tuberculosis Upon Patients‘ Quality Of Life Who Undergo Directly Observed Treatment Short Course(DOTS) In AL-Amarah City. Journal ofKufa for Nursing Science. 2014;1(4).
24. Shishehgar, F., Ramezani Tehrani, F., Mirmiran, P., Hajian, S., & Baghestani, A. R. (2016). Comparison of the association of excess weight on health related quality of life of women with polycystic ovary syndrome: An age- and BMI-matched case control study. PLoS ONE, 11(10), 1–11. https://doi-org.ezproxy.okcu.edu/10.1371/journal.pone.016291
25. Stein IF, Leventhal ML. Amenorrhea associated with bilateral polycystic ovaries. American Journal of Obstetrics and Gynecology. 1935;29(2):181–91.
26. Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, et al. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertility and Sterility [Internet]. 2018 Aug;110(3):364–79. Available from: https://www.fertstert.org/article/S0015-0282(18)30400-X/pdf
27. The Rotterdam ESHRE/ASRM‐sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Human Reproduction. 2004 Jan 1;19(1):41–7.
28. Yaqoub R, Abdulwahid H. Self-body Image and its Association to Quality of Life among Women Undergoing to Mastectomy. Oncology and Radiotherapy. 2023;17(7):213–6.