Prevalence and Management of Peptic Ulcers in Pregnant Women in Baghdad

Taha Qasim  Ahnad

Taha Qasim Ahnad Forensic pathologist MBCHB/MSc. Al-Farabi University Collage, Baghdad, Iraq

Keywords: Peptic ulcer, Pregnancy, Infection, Complication, Odds ratio

Abstract

Peptic ulcers in pregnant women pose a therapeutic challenge due to the need to balance treatment efficacy with fetal safety. This study aimed to explore the prevalence, causes, symptoms, and management strategies of peptic ulcers among pregnant women. The research involved 140 pregnant participants from various hospitals and clinics, confirmed through clinical and laboratory examinations. Data collection was conducted via a validated questionnaire covering demographics, medical and family history, dietary habits, and lifestyle factors. Results indicated a 2% prevalence of peptic ulcers among the participants, with Helicobacter pylori infection, NSAID use, and psychological distress identified as significant risk factors. Symptoms included stomach pain, nausea, heartburn, and acid reflux. Management strategies emphasized lifestyle modifications, cautious use of antacids and antibiotics, and stress management techniques. Findings highlighted the need for careful treatment planning and ongoing research to improve care for pregnant women with peptic ulcers.

References

E. Sverden, et al., "Peptic Ulcer Disease," BMJ, vol. 367, 2019.

P. Malfertheiner and C. Schulz, "Peptic Ulcer: Chapter Closed?," Digestive Diseases, vol. 38, no. 2, pp. 112-116, 2020.

B. C. Yegen, "Lifestyle and Peptic Ulcer Disease," Current Pharmaceutical Design, vol. 24, no. 18, pp. 2034-2040, 2018.

T. D. Jidha, et al., "Perforated Duodenal Ulcer in the Third Trimester of Pregnancy, With Survival of Both the Mother and Neonate, in Ethiopia: A Case Report," Journal of Medical Case Reports, vol. 16, no. 1, p. 322, 2022.

G. Bereda, "Peptic Ulcer Disease: Definition, Pathophysiology, and Treatment," Journal of Biomedical and Biological Sciences, vol. 1, no. 2, pp. 1-10, 2022.

K. Jaswanth, K. Kumar, and P. Venkatesh, "A Review on Peptic Ulcer," UPI Journal of Pharmaceutical, Medical and Health Sciences, pp. 19-26, 2022.

A. E. Dumitru, et al., "Peptic Ulcer Disease During Pregnancy," Romanian Medical Journal, vol. 69, no. 2, p. 59, 2022.

K. Dunbar, R. Yadlapati, and V. Konda, "Heartburn, Nausea, and Vomiting During Pregnancy," Official Journal of the American College of Gastroenterology, vol. 117, no. 10S, pp. 10-15, 2022.

C. Rosen, et al., "Management and Outcomes of Peptic Ulcer Disease in Pregnancy," Obstetrics & Gynecology, vol. 133, pp. 41S, 2019.

C. Rosen, et al., "Management and Outcomes of Peptic Ulcer Disease in Pregnancy," The Journal of Maternal-Fetal & Neonatal Medicine, vol. 34, no. 9, pp. 1368-1374, 2021.

C. Rosen, et al., "Pregnancy Outcomes Among Women With Peptic Ulcer Disease," Journal of Perinatal Medicine, vol. 48, no. 3, pp. 209-216, 2020.

E. I. Umegbolu, "Spike in Peptic Ulcer Disease in Pregnancy in a Rural Community of Enugu State, Southeast Nigeria: Is This an Epidemic?," International Journal of Community Medicine and Public Health, vol. 9, no. 12, pp. 4359, 2022.

L. Kamani, et al., "Safety of Endoscopy and Its Outcome in Pregnancy," Cureus, vol. 11, no. 12, 2019.

E. C. Liao, et al., "A Pilot Study of Non-Invasive Diagnostic Tools to Detect Helicobacter Pylori Infection and Peptic Ulcer Disease," Scientific Reports, vol. 13, no. 1, p. 22800, 2023.

M. A. H. Ali, et al., "The Impact of Helicobacter Pylori Infection on Iron Deficiency Anemia in Pregnancy," Iraqi Journal of Hematology, vol. 6, no. 2, pp. 60-64, 2017.

M. A. Haque, et al., "Prevalence and the Outcome of Peptic Ulcer Disease-A Retrospective Study," Medico Research Chronicles, vol. 9, no. 6, pp. 370-377, 2022.