Using Safranine Dye for Indirect Spectrophotometric Determination of Furosemide in the Presence N-bromosuccinamide
Keywords:
safranine dye, furosemide, N-bromosuccinamide
Abstract
A sensitive and accurate indirect spectroscopic method has been proposed for the determination of furosemide in acidic media. The method includes oxidation of safranin dye in the presence of N-bromosuccinimide as an oxidizing agent to form a pink-colored product that can be measured spectrophotometrically at a wavelength of 526 nm. The molar absorbance and Sandel sensitivity were (2.4×104 L/mol.cm) and (0.0135 µg\cm) respectively, the correlation coefficient was 0.9995 with a recovery rate of 97.24%, a standard deviation of 0.867%, 0.0966 µg\ml for (LOD) and 0.322 µg\ml for (LOQ). The technique was applied to determine the purity of furosemide and the medicinal forms of it.
References
Merck index, 13th Edition. USA: Merck and Co, 2006.
G. J. Kher, “ ,” Saurashtra University, 2011.
M. Thevis, T. Kuuranne, and H. Geyer, “Annual banned‐substance review: Analytical approaches in human sports drug testing 2019/2020,” Drug Test Anal, 2021, doi: 10.1002/dta.2969.
M. E. Bosch, A. J. R. Sánchez, F. S. Rojas, and ..., “Analytical methodologies for the determination of cisplatin,” Journal of pharmaceutical …, 2008, [Online]. Available: https://www.sciencedirect.com/science/article/pii/S0731708508001003
J. Fischer and C. R. Ganellin, “Analogue-based drug discovery,” Chemistry International–Newsmagazine for …, 2010, doi: 10.1515/ci.2010.32.4.12.
F. J. Al-Shammary, N. A. A. Mian, and M. S. Mian, “Analytical Profiles of Drug Substances and Excipients,” Naproxen, 1992.
R. N. Brogden, R. C. Heel, T. M. Speight, and G. S. Avery, “Sucralfate: a review of its pharmacodynamic properties and therapeutic use in peptic ulcer disease,” Drugs, 1984, doi: 10.2165/00003495-198427030-00002.
K. Basavaiah, “Spectrophotometric determination of furosemide in pharmaceuticals using permanganate,” Jordan Journal of Chemistry (JJC), 2009, [Online]. Available: https://jjc.yu.edu.jo/index.php/jjc/article/download/319/616
M. E. M. Hassouna, Y. M. Issa, and A. G. Zayed, “Spectrophotometric determination of furosemide drug in different formulations using Schiff’s bases,” Forensic Res Criminol Int J, 2015, [Online]. Available: https://www.researchgate.net/profile/Mohamed-Hassouna-6/publication/345838827_Spectrophotometric_Determination_of_Furosemide_Drug_in_Different_Formulations_using_Schiff_’s_Bases/links/618c29763068c54fa5cd734a/Spectrophotometric-Determination-of-Furosemide-Drug-in-Different-Formulations-using-Schiff-s-Bases.pdf
M. E. Bosch, A. J. R. Sánchez, F. S. Rojas, and C. B. Ojeda, “Analytical determination of furosemide: the last researches,” Int J Pharm Biol Sci, 2013, [Online]. Available: http://ijpbs.com/ijpbsadmin/upload/ijpbs_52cfc8f28d73d.pdf
S. A. Darweesh, “Simultaneous Determination of Sulfanilamide and Furosemide by Using Derivative Spectrophotometry,” Ibn AL-Haitham Journal For Pure and Applied Science, 2017, [Online]. Available: https://www.iasj.net/iasj/download/8d01a467f2571a41
M. E. M. Hassouna, Y. M. Issa, and A. G. Zayed, “Spectrophotometric determination of furosemide drug in different formulations using Schiff’s bases,” Forensic Res Criminol Int J, 2015, [Online]. Available: https://www.researchgate.net/profile/Mohamed-Hassouna-6/publication/345838827_Spectrophotometric_Determination_of_Furosemide_Drug_in_Different_Formulations_using_Schiff_’s_Bases/links/618c29763068c54fa5cd734a/Spectrophotometric-Determination-of-Furosemide-Drug-in-Different-Formulations-using-Schiff-s-Bases.pdf
F. K. Omar and H. S. Mahmod, AN INDIRECT SPECTROPHOTOMETRIC DETERMINATION OF FUROSEMIDE IN PHARMACEUTICAL PREPARATIONS. wjpr.s3.ap-south-1.amazonaws.com, 2018. [Online]. Available: https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1536043542.pdf
M. M. S. Okdeh and A. Aljalfah, New Method for Spectrophotometric Determination of Furosemide in Pure Form and in Pharmaceutical Formulations. aipublications.com, 2022. [Online]. Available: https://aipublications.com/uploads/issue_files/2IJCMP-APR20231-NewMethod.pdf
A. F. Qader and N. A. Fakhre, “Spectrofluorometric determination of furosemide in some pharmaceutical product using acriflavine as a reagent,” AIP Conf Proc, 2017, doi: 10.1063/1.5004319/13559367/020042_1_online.
A. M. K. Ahmed and Z. T. W. Ahmed, “Estimation of Furosemide Spectrophotometrically in Pharmaceutical preparations by Oxidative Coupling Reaction,” Tikrit Journal of Pure Science, 2022, [Online]. Available: https://www.iasj.net/iasj/download/3dc8da8cc908fecd
F. S. Semaan and E. T. G. Cavalheiro, “Spectrophotometric determination of furosemide based on its complexation with Fe (III) in ethanolic medium using a flow injection procedure,” Anal Lett, 2006, [Online]. Available: https://www.researchgate.net/profile/Felipe-Semaan/publication/244601326_Spectrophotometric_Determination_of_Furosemide_Based_on_Its_Complexation_with_FeIII_in_Ethanolic_Medium_Using_a_Flow_Injection_Procedure/links/56cb1b9f08ae1106370b70b3/Spectrophotometric-Determination-of-Furosemide-Based-on-Its-Complexation-with-FeIII-in-Ethanolic-Medium-Using-a-Flow-Injection-Procedure.pdf
M. S. Kaynak, E. Akgeyik, M. Ates, and ..., “Development of HPLC methods for individual determination of 20 active pharmaceutical ingredients for ussing-chamber studies,” Current …, 2017, [Online]. Available: https://www.ingentaconnect.com/content/ben/cpa/2017/00000013/00000002/art00009
S. Sharma and M. Phale, “Stress degradation studies of furosemide and development and validation of SIAM RP-HPLC method for its quantification,” World J. Pharm. Res, 2017, [Online]. Available: https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1493456409.pdf
J. S. Shaikh and N. N. Rao, “Simultaneous estimation and forced degradation studies of amiloride hydrochloride and furosemide in a pharmaceutical dosage form using reverse-phase high …,” Asian J. Pharm. Clin. Res, 2018, [Online]. Available: https://www.academia.edu/download/87479598/15048.pdf
R. R. Chavan, S. D. Bhinge, M. A. Bhutkar, D. S. Randive, and ..., “Method development and validation of spectrophotometric and RP-HPLC methods for simultaneous estimation of spironolactone and furosemide in bulk and …,” Anal. Sci …, 2021, [Online]. Available: https://www.academia.edu/download/97957969/JAKO202130637228835.pdf
J. N. Tandel, “Development and validation of RP-Hplc method for the Simultaneous Determination of amiloride hydro chloride and Furosemide in pure and pharmaceutical …,” Eurasian Journal of Analytical Chemistry, 2017, [Online]. Available: https://pdfs.semanticscholar.org/68ec/2decdeb39baac60e03f3516921d2417f0775.pdf
M. S. Arayne, S. Naveed, and N. Sultana, “A Validated Reverse Phase Liquid Chromatographic Method for Simultaneous Analysis of Enalapril Maleate, Hydrochlorothiazide and Furosemide in Active …,” Pharm Anal Acta, 2013, [Online]. Available: https://www.academia.edu/download/33255955/23_ENP_DIUREC_PAA.pdf
N. R. Ahmed, “Estimation of Furosemide in Pharmaceutical Preparation Samples,” International Journal Forensic Res., vol. 1, no. 1, pp. 34–37, 2020.
S. W. Oh and S. Y. Han, “Loop diuretics in clinical practice,” Electrolytes &Blood Pressure: E &BP, 2015, [Online]. Available: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520883/
N. P. Shetti, L. V Sampangi, R. N. Hegde, and ..., “Electrochemical oxidation of loop diuretic furosemide at gold electrode and its analytical applications,” International Journal of …, 2009, [Online]. Available: https://www.sciencedirect.com/science/article/pii/S1452398123151406
S. J. Malode, J. C. Abbar, N. P. Shetti, and S. T. Nandibewoor, “Voltammetric oxidation and determination of loop diuretic furosemide at a multi-walled carbon nanotubes paste electrode,” Electrochim Acta, 2012, [Online]. Available: https://www.sciencedirect.com/science/article/pii/S0013468611016641
S. D. Bukkitgar and N. P. Shetti, “Electrochemical oxidation of loop diuretic furosemide in aqueous acid medium and its analytical application,” Cogent Chem, 2016, doi: 10.1080/23312009.2016.1152784.
S. Katsura, N. Yamada, A. Nakashima, and ..., “Investigation of discoloration of furosemide tablets in a light-shielded environment,” Chemical and …, 2017, [Online]. Available: https://www.jstage.jst.go.jp/article/cpb/65/4/65_c16-00835/_article/-char/ja/
R. Teraoka, T. Fukami, T. Furuishi, H. Nagase, and ..., “Improving the solid-state photostability of furosemide by its cocrystal formation,” Chemical and …, 2019, [Online]. Available: https://www.jstage.jst.go.jp/article/cpb/67/9/67_c18-00812/_html/-char/en
Y. A. Abbasi, S. Shahida, A. Ali, and M. H. Khan, “Liquid–liquid extraction of mercury (II) from aqueous solution using furosemide in benzyl alcohol,” … of Radioanalytical and Nuclear …, 2019, doi: 10.1007/s10967-018-6400-5.
S. K. Koh, J. W. Jeong, S. I. Choi, R. M. Kim, T. S. Koo, and ..., “Pharmacokinetics and diuretic effect of furosemide after single intravenous, oral tablet, and newly developed oral disintegrating film administration in healthy …,” BMC Veterinary …, 2021, doi: 10.1186/s12917-021-02998-4.
M. A. Abro, F. A. Mangi, and D. A. Jamro, “… Kalhoro, Aijaz Ali Otho &Abdul Qayoom Mugheri (2021) Electrochemical Biosensor Based on Furosemide-Gold Nanoparticles for The Determination of …,” J Chem Edu Res Prac 5: 36.
G. J. Kher, “ ,” Saurashtra University, 2011.
M. Thevis, T. Kuuranne, and H. Geyer, “Annual banned‐substance review: Analytical approaches in human sports drug testing 2019/2020,” Drug Test Anal, 2021, doi: 10.1002/dta.2969.
M. E. Bosch, A. J. R. Sánchez, F. S. Rojas, and ..., “Analytical methodologies for the determination of cisplatin,” Journal of pharmaceutical …, 2008, [Online]. Available: https://www.sciencedirect.com/science/article/pii/S0731708508001003
J. Fischer and C. R. Ganellin, “Analogue-based drug discovery,” Chemistry International–Newsmagazine for …, 2010, doi: 10.1515/ci.2010.32.4.12.
F. J. Al-Shammary, N. A. A. Mian, and M. S. Mian, “Analytical Profiles of Drug Substances and Excipients,” Naproxen, 1992.
R. N. Brogden, R. C. Heel, T. M. Speight, and G. S. Avery, “Sucralfate: a review of its pharmacodynamic properties and therapeutic use in peptic ulcer disease,” Drugs, 1984, doi: 10.2165/00003495-198427030-00002.
K. Basavaiah, “Spectrophotometric determination of furosemide in pharmaceuticals using permanganate,” Jordan Journal of Chemistry (JJC), 2009, [Online]. Available: https://jjc.yu.edu.jo/index.php/jjc/article/download/319/616
M. E. M. Hassouna, Y. M. Issa, and A. G. Zayed, “Spectrophotometric determination of furosemide drug in different formulations using Schiff’s bases,” Forensic Res Criminol Int J, 2015, [Online]. Available: https://www.researchgate.net/profile/Mohamed-Hassouna-6/publication/345838827_Spectrophotometric_Determination_of_Furosemide_Drug_in_Different_Formulations_using_Schiff_’s_Bases/links/618c29763068c54fa5cd734a/Spectrophotometric-Determination-of-Furosemide-Drug-in-Different-Formulations-using-Schiff-s-Bases.pdf
M. E. Bosch, A. J. R. Sánchez, F. S. Rojas, and C. B. Ojeda, “Analytical determination of furosemide: the last researches,” Int J Pharm Biol Sci, 2013, [Online]. Available: http://ijpbs.com/ijpbsadmin/upload/ijpbs_52cfc8f28d73d.pdf
S. A. Darweesh, “Simultaneous Determination of Sulfanilamide and Furosemide by Using Derivative Spectrophotometry,” Ibn AL-Haitham Journal For Pure and Applied Science, 2017, [Online]. Available: https://www.iasj.net/iasj/download/8d01a467f2571a41
M. E. M. Hassouna, Y. M. Issa, and A. G. Zayed, “Spectrophotometric determination of furosemide drug in different formulations using Schiff’s bases,” Forensic Res Criminol Int J, 2015, [Online]. Available: https://www.researchgate.net/profile/Mohamed-Hassouna-6/publication/345838827_Spectrophotometric_Determination_of_Furosemide_Drug_in_Different_Formulations_using_Schiff_’s_Bases/links/618c29763068c54fa5cd734a/Spectrophotometric-Determination-of-Furosemide-Drug-in-Different-Formulations-using-Schiff-s-Bases.pdf
F. K. Omar and H. S. Mahmod, AN INDIRECT SPECTROPHOTOMETRIC DETERMINATION OF FUROSEMIDE IN PHARMACEUTICAL PREPARATIONS. wjpr.s3.ap-south-1.amazonaws.com, 2018. [Online]. Available: https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1536043542.pdf
M. M. S. Okdeh and A. Aljalfah, New Method for Spectrophotometric Determination of Furosemide in Pure Form and in Pharmaceutical Formulations. aipublications.com, 2022. [Online]. Available: https://aipublications.com/uploads/issue_files/2IJCMP-APR20231-NewMethod.pdf
A. F. Qader and N. A. Fakhre, “Spectrofluorometric determination of furosemide in some pharmaceutical product using acriflavine as a reagent,” AIP Conf Proc, 2017, doi: 10.1063/1.5004319/13559367/020042_1_online.
A. M. K. Ahmed and Z. T. W. Ahmed, “Estimation of Furosemide Spectrophotometrically in Pharmaceutical preparations by Oxidative Coupling Reaction,” Tikrit Journal of Pure Science, 2022, [Online]. Available: https://www.iasj.net/iasj/download/3dc8da8cc908fecd
F. S. Semaan and E. T. G. Cavalheiro, “Spectrophotometric determination of furosemide based on its complexation with Fe (III) in ethanolic medium using a flow injection procedure,” Anal Lett, 2006, [Online]. Available: https://www.researchgate.net/profile/Felipe-Semaan/publication/244601326_Spectrophotometric_Determination_of_Furosemide_Based_on_Its_Complexation_with_FeIII_in_Ethanolic_Medium_Using_a_Flow_Injection_Procedure/links/56cb1b9f08ae1106370b70b3/Spectrophotometric-Determination-of-Furosemide-Based-on-Its-Complexation-with-FeIII-in-Ethanolic-Medium-Using-a-Flow-Injection-Procedure.pdf
M. S. Kaynak, E. Akgeyik, M. Ates, and ..., “Development of HPLC methods for individual determination of 20 active pharmaceutical ingredients for ussing-chamber studies,” Current …, 2017, [Online]. Available: https://www.ingentaconnect.com/content/ben/cpa/2017/00000013/00000002/art00009
S. Sharma and M. Phale, “Stress degradation studies of furosemide and development and validation of SIAM RP-HPLC method for its quantification,” World J. Pharm. Res, 2017, [Online]. Available: https://wjpr.s3.ap-south-1.amazonaws.com/article_issue/1493456409.pdf
J. S. Shaikh and N. N. Rao, “Simultaneous estimation and forced degradation studies of amiloride hydrochloride and furosemide in a pharmaceutical dosage form using reverse-phase high …,” Asian J. Pharm. Clin. Res, 2018, [Online]. Available: https://www.academia.edu/download/87479598/15048.pdf
R. R. Chavan, S. D. Bhinge, M. A. Bhutkar, D. S. Randive, and ..., “Method development and validation of spectrophotometric and RP-HPLC methods for simultaneous estimation of spironolactone and furosemide in bulk and …,” Anal. Sci …, 2021, [Online]. Available: https://www.academia.edu/download/97957969/JAKO202130637228835.pdf
J. N. Tandel, “Development and validation of RP-Hplc method for the Simultaneous Determination of amiloride hydro chloride and Furosemide in pure and pharmaceutical …,” Eurasian Journal of Analytical Chemistry, 2017, [Online]. Available: https://pdfs.semanticscholar.org/68ec/2decdeb39baac60e03f3516921d2417f0775.pdf
M. S. Arayne, S. Naveed, and N. Sultana, “A Validated Reverse Phase Liquid Chromatographic Method for Simultaneous Analysis of Enalapril Maleate, Hydrochlorothiazide and Furosemide in Active …,” Pharm Anal Acta, 2013, [Online]. Available: https://www.academia.edu/download/33255955/23_ENP_DIUREC_PAA.pdf
N. R. Ahmed, “Estimation of Furosemide in Pharmaceutical Preparation Samples,” International Journal Forensic Res., vol. 1, no. 1, pp. 34–37, 2020.
S. W. Oh and S. Y. Han, “Loop diuretics in clinical practice,” Electrolytes &Blood Pressure: E &BP, 2015, [Online]. Available: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520883/
N. P. Shetti, L. V Sampangi, R. N. Hegde, and ..., “Electrochemical oxidation of loop diuretic furosemide at gold electrode and its analytical applications,” International Journal of …, 2009, [Online]. Available: https://www.sciencedirect.com/science/article/pii/S1452398123151406
S. J. Malode, J. C. Abbar, N. P. Shetti, and S. T. Nandibewoor, “Voltammetric oxidation and determination of loop diuretic furosemide at a multi-walled carbon nanotubes paste electrode,” Electrochim Acta, 2012, [Online]. Available: https://www.sciencedirect.com/science/article/pii/S0013468611016641
S. D. Bukkitgar and N. P. Shetti, “Electrochemical oxidation of loop diuretic furosemide in aqueous acid medium and its analytical application,” Cogent Chem, 2016, doi: 10.1080/23312009.2016.1152784.
S. Katsura, N. Yamada, A. Nakashima, and ..., “Investigation of discoloration of furosemide tablets in a light-shielded environment,” Chemical and …, 2017, [Online]. Available: https://www.jstage.jst.go.jp/article/cpb/65/4/65_c16-00835/_article/-char/ja/
R. Teraoka, T. Fukami, T. Furuishi, H. Nagase, and ..., “Improving the solid-state photostability of furosemide by its cocrystal formation,” Chemical and …, 2019, [Online]. Available: https://www.jstage.jst.go.jp/article/cpb/67/9/67_c18-00812/_html/-char/en
Y. A. Abbasi, S. Shahida, A. Ali, and M. H. Khan, “Liquid–liquid extraction of mercury (II) from aqueous solution using furosemide in benzyl alcohol,” … of Radioanalytical and Nuclear …, 2019, doi: 10.1007/s10967-018-6400-5.
S. K. Koh, J. W. Jeong, S. I. Choi, R. M. Kim, T. S. Koo, and ..., “Pharmacokinetics and diuretic effect of furosemide after single intravenous, oral tablet, and newly developed oral disintegrating film administration in healthy …,” BMC Veterinary …, 2021, doi: 10.1186/s12917-021-02998-4.
M. A. Abro, F. A. Mangi, and D. A. Jamro, “… Kalhoro, Aijaz Ali Otho &Abdul Qayoom Mugheri (2021) Electrochemical Biosensor Based on Furosemide-Gold Nanoparticles for The Determination of …,” J Chem Edu Res Prac 5: 36.
Published
2024-03-23
How to Cite
Al-Taee, M. M., & Al-Enizzi, M. S. (2024). Using Safranine Dye for Indirect Spectrophotometric Determination of Furosemide in the Presence N-bromosuccinamide. Central Asian Journal of Medical and Natural Science, 5(2), 60-71. Retrieved from https://cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/2401
Section
Articles
