L. Serriola's Protective Impact on Lung Histology Against Benzo(A)Pyrene-Induced Carcinogenesis in Mice
Abstract
Natural plants are considered an important factor in human resistance to diseases.
This study aimed to evaluate Protective effect of L. serriole on histological features of Lungs
induced by a carcinogen benzo (a) pyrene. The histological study of the lungs of mice
showed that there were significant changes in the normal liver structure in the group of
animals that took doses of the carcinogenic substance benzo(a)pyrene, which caused damage to the lung tissue. A disease in the normal structure of the lung tissue in a normal way.
The results of the histological diagnosis of the lung showed the presence of hyperemia at
the concentration dose of 0.003 mg/kg. When the concentration was given at 0.0015 mg/kg,
it was found that there were histological changes, infiltration of inflammatory cells, compared to the control group .The results of changes in the measurements of internal parameters of the lungs in the group that was taken with a carcinogen benzo(a)pyrene only
showed a significant increase at the level of probability 0.05 in the average measurements
of the internal parameters of the alveoli and bronchi, while the results of the dose of alcoholic extract of wild beer lettuce showed a concentration of 0.006 mg/kg, 0.003 mg/kg, and
0.0015 mg/kg showed a slight increase at a probability level of 0.05 compared to the control
group.
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