COMPARATIVE ANALYSIS OF STRUCTURAL AND FUNCTIONAL INDICATORS OF THE HEART IN PATIENTS WITH ATRIAL FIBRILLATION DUE TO MYOCARDIAL INFARCTION OF DIFFERENT LOCATIONS
Abstract
Large epidemiological studies have shown that AF is associated with high mortality and adverse events in patients with AMI. However, the answer of this association is still not clear. According to the literature, atrial fibrillation (AF) complicates the course of myocardial infarction (MI) in 1213% of patients. The appearance of arrhythmia is associated with a worsening prognosis of the disease. Against the background of tachysystole , which often develops with AF, coronary blood flow is depleted and acute heart failure appears. The absence of coordinated atrial systole during fibrillation plays an important role in the development of hemodynamic complications, because the atrial component of diastole provides up to 25% of left ventricular (LV) filling. One of the main reasons for the development of AF during myocardial infarction is considered to be an increase in the hemodynamic load on the atrium with the development of acute left ventricular failure. Against the background of pressure overload, overstrain and stretching of the atrial myocardium occurs, which significantly increases its electrical instability. In addition to acute hemodynamic overload, the causes of AF include ischemia and damage to the atrial myocardium in the case of thrombotic occlusion above the origin of the arteries supplying the atria. After the cessation of the arrhythmia attack, as a rule, hemodynamics and coronary blood flow improve. However, in the case of persistent dysfunction of the left atrium (LA), the risk of distant reversion thromboembolism of the systemic circulation remains.
References
2. Abdulloeva M., Nasyrova Z. RISK STRATIFICATION AND INTENSIVE CARE OF PATIENTS WITH ACUTE CORONARY SYNDROME WITHOUT ST SEGMENT ELEVATION IN CLINICAL PRACTICE //Collection of scientific papers «SCIENTIA». – 2023. – №. February 3, 2023; Chicago, USA. – С. 205-206.
3. Пулатова К. С. Влияние Антигипертензивных Препаратов На Инсулинорезистентность И Показателей Липидного Спектра //European Journal Of Interdisciplinary Research And Development. – 2023. – Т. 15. – С. 72-75.
4. Dilshodovna A. M., Odylovna K. F., Samveilovna P. K. Peculiarities of Psychological Disorders in Patients with Acute Coronary Syndrome //International Journal of Health Systems and Medical Sciences. – 2022. – Т. 1. – №. 6. – С. 203-207.
5. Tashkenbaeva E. N., Pulatova K. S., Yorbulov L. S. Evaluation of Echocardiography in Patients With Coronary Heart Disease Combined With Metabolic Syndrome //Central Asian Journal of Medical and Natural Science. – 2022. – Т. 3. – №. 6. – С. 194-197.