Characteristics Of Liver Marker Indicators Cholecystokinin-8 And Gastrin-17 In Patients With V Virus Liver Cirrhosis

  • M.A. Juraeva Andijan State Medical Institute
  • N.S. Mamasoliev Andijan State Medical Institute
  • N.D. Ashuralieva Andijan State Medical Institute
Keywords: liver cirrhosis, prophylaxis, short-chain peptides, V virus, stomach

Abstract

According to predictions of the World Health Organization (WHO), despite the advances in modern therapy and the development of liver transplantation in recent years, the death rate from liver diseases is expected to double in the next 10-20 years. According to this authoritative organization, approximately 200 million patients suffer from chronic liver diseases.

In our country, more than 50,000 people die from cirrhosis of the liver every year, and this is 3 times higher than the death rate.

The purpose of the study: to study the etiological, epidemiological, clinical and diagnostic characteristics of liver cirrhosis among rural residents of Andijan region, to improve the preventive measures of liver cirrhosis. In order to implement the goals and tasks set before us, the prevalence of chronic liver and gastrointestinal system diseases among the rural population of Markhamat district of Andijan region was studied retrospectively based on the data of 2017-2022.

References

1. Adriaenssens, A., Lam, BYH, Billing, L., Skeffington, K., Sewing, S., Reimann, F., & Gribble, F.A transcriptome-led exploration of molecular mechanisms regulating somatostatin-producing D-cells in the gastric epithelium //Endocrinology. – 2015. – V. 156. – №. 11. – P. 3924-3933;
2. Hoffmaster K.A, Zamek-Gliszczynski MJ, Pollack GM, Brouwer KL. Hepatobiliary disposition of the metabolically stable opioid peptide [D-Pen2, D-Pen5]-enkephalin (DPDPE): pharmacokinetic consequences of the interplay between multiple transport system. J. Pharmacol. Exp. Ther., 2004, vol. 311(3), P.1204-1208
3. Huynh D., Nguyen N. Q. Gastrointestinal Dysfunction in Chronic Liver Disease //J Gastrointest Dig Syst. – 2015.- vol. 5, no 257,- P. 1-3.;
4. Katsusuke S., Takeuchi T., Watanabe S., Nishiwaki, H. Postprandial plasma cholecystokinin response in patients after gastrectomy and pancreatoduodenectomy. Am J Gastroenterol, 2008, vol. 81, P. 1038-1040.;
5. Katsusuke S., Takeuchi T., Watanabe S., Nishiwaki, H. Postprandial plasma cholecystokinin response in patients after gastrectomy and pancreatoduodenectomy. Am J Gastroenterol, 2008, vol. 81, P. 1038-1040
6. Mazaki-Tovi, M., Segev, G., Yas-Natan, E., & Lavy, E.Serum gastrin concentrations in dogs with liver disorders //Veterinary Record. – 2012. – Vol. 171. – №. 1. – Р. 19-26; 255, б. 880-883;
7. Rehfeld J. F. Cholecystokinin—from local gut hormone to ubiquitous messenger //Frontiers in endocrinology. – 2017. – V. 8. – P. 47-50.
8. Valentini, L., Schuetz, T., Omar, A., Gläser, S., Kasim, E., Nowotny, P., ...&Ockenga, J. Abnormal plasma peptide YY3–36 levels in patients with liver cirrhosis //Nutrition. – 2011. – V. 27. – №. 9. – P. 880-884
9. Babich S. M., Aleynik V.A. Changes in gastric secretion when pentagastrin and leu-enkephalin are injected into the peripheral and portal veins//Postgraduate doctor, - Voronezh,- 2010.- № 5,2 (42).- Pp. 252-253;
10. Korotko G. F. Proteolysis in the regulation of digestive system functions //Experimental and clinical gastroenterology. - 2013. – No. 10. –pp. 24-26
Published
2023-11-22
How to Cite
Juraeva, M., Mamasoliev , N., & Ashuralieva, N. (2023). Characteristics Of Liver Marker Indicators Cholecystokinin-8 And Gastrin-17 In Patients With V Virus Liver Cirrhosis. Central Asian Journal of Medical and Natural Science, 4(6), 535-539. https://doi.org/10.17605/cajmns.v4i6.2079
Section
Articles