Study of some biochemical parameters for patients withType II Diabetes Mellitus in Al Rifai district

  • Zahraa Arhym Sabar University of Sumer – College of Science Department of pathological analyzes
  • Fatima Karim University of Sumer – College of Science Department of pathological analyzes
Keywords: DM, lipid, Dhi-qar

Abstract

Diabetes type second, constitutes a major threat to the health of public, and not ideal it control leads to chronic high level of glucose in the blood, the cause of this type occur due to either resistant cells of the body to the action of insulin hormone, or may be due to the lack of produce adequate amount of insulin from before the pancreas, the spectrum is caused by multiple factors, most notably, weight gain and lack of physical activity .

Symptoms include this disease excessive urination and thirst, constant hunger, weight loss, blurred vision and fatigue. These symptoms may appear suddenly. Diabetes can cause O over time damage to the heart, blood vessels, eyes, kidneys and nerves. second type of diabetes the beta cells are producing insulin naturally, they may also produce a larger quantity, but not be enough to glucose metabolism in the body. This study was conducted in the laboratory of the year Rifai were examined blood samples for patients with diabetes.

These are designed to determine the levels of study  (Glucose- Cholesterol _ Triglyceride )It was divided on the basis of the measured calibrator:

1_healthy control aged (15_30) number 20.

2_Diabetic patient  aged (15_30) and the number 40.

Where section by women and men were compared between the proportions of healthy and disease show me the results of a significant increase in concentrations (Glucose_ Cholesterol _ Triglyceride ) Compared with healthy and there is also the effect of sex.There are other factors that affect the patient's environment, heh, and his condition for social and Inherit patients and injury to blood pressure.

References

1. Zou Q, Qu K, Luo Y, Yin D, Ju Y, Tang H. Predicting Diabetes Mellitus With Machine Learning Techniques. Frontiers in Genetics. 2018;9(515).
2. Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nature Reviews Endocrinology. 2018;14(2):88-98.
3. Oguntibeju OO. Type 2 diabetes mellitus, oxidative stress andinflammation: examining the links. International journal of physiology, pathophysiology and pharmacology. 2019;11(3):45.
4. Glovaci D, Fan W, Wong ND. Epidemiology of diabetes mellitus and cardiovascular disease. Current cardiology reports. 2019;21(4):1-8.
5. Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J. Epidemiology of type 2 diabetes–global burden of disease and forecasted trends. Journal of epidemiology and global health. 2020;10(1):107.
6. Abusaib M, Ahmed M, Nwayyir HA, Alidrisi HA, Al-Abbood M, Al- Bayati A, et al. Iraqi experts consensus on the management of type 2 diabetes/prediabetes in adults. Clinical Medicine Insights: Endocrinology and Diabetes. 2020;13:1179551420942232.
7. Hirsch IB, Juneja R, Beals JM, Antalis CJ, Wright Jr EE. The evolution of Insulin and how it informs therapy and treatment choices. Endocrine reviews. 2020;41(5):733-55.
8. Petersen MC, Shulman GI. Mechanisms of insulin action and insulin Resistance. Physiological reviews. 2018;98(4):2133-223.
9. Jaiswal, M.; Schinske, A.; Busui, R.P. Lipids and lipid management in diabetes. Best Pract. Res. Clin.Endocrinol. Metab. 2014, 28, 325–328. [CrossRef] [PubMed]
10. Catapano, A.L.; Graham, I.; De Backer, G.; Wiklund, O.; Chapman, M.J.; Drexel, H.; Hoes, A.W.; Jennings, C.S.;Landmesser, U.; Pedersen, T.R.; et al. 2016 ESC/EAS guidelines for the management of dyslipidaemias.0Eur. Heart J. 2016, 37, 2999–3058. [CrossRef] [PubMed]
11. Alalwan, T.A.; Perna, S.; Mandeel, Q.A.; Abdulhadi, A.; Alsayyad, A.S.; D’Antona, G.; Negro, M.; Riva, A.; Petrangolini, G.; Allegrini, P.; et al. Effects of Daily Low-Dose Date Consumption on Glycemic Control,Lipid Profile, and Quality of Life in Adults with Pre- and Type 2 Diabetes: A Randomized Controlled Trial.Nutrients 2020, 12, 217. [CrossRef] [PubMed]
12. Basu, A. Role of Berry Bioactive Compounds on Lipids and Lipoproteins in Diabetes and Metabolic Syndrome.Nutrients 2019, 11, 1983. [CrossRef]
13. Silvio, E.I.; Richard, M.B.; John, B.B.; Michaela, D.; Ele, F.; Michael, N.; Anne, L.P.; Apostolos, T.; Richard, W.; David, R.M. Management of Hyperglycaemia in Type 2 Diabetes, 2015: A Patient-Centred Approach. Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 2015, 58, 429–442.
14. Artha, I.M.J.R.; Bhargah, A.; Dharmawan, N.K.; Pande, U.W.; Triyana, K.A.; Mahariski, P.A.; Yuwono, J.;Bhargah, V.; Prabawa, I.P.Y.; Manuaba, I.B.A.P.; et al. High level of individual lipid profile and lipid ratio as a predictive marker of poor glycemic control in type-2 diabetes mellitus. Vasc. Health Risk Manag. 2019, 15,149–157. [CrossRef]
15. Drew, B.G.; Duffy, S.J.; Formosa, M.F.; Natoli, A.K.; Henstridge, D.C.; Penfold, S.A.; Thomas, W.G.; Mukhamedova, N.; de Courten, B.; Forbes, J.M.; et al. High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus. Circulation 2009, 119, 2103–2111. [CrossRef]
16. J, Hameed B, Das G, Siddiqui MA, Ahmad I (2005). Postprandial hypertriglyceridemia and carotid intima – media thickness in north Indian type 2 diabetic subjects. Diabetes Res Clin Pract 69:142-50. Aisen, P. (1984). Transferrin metabolism and the liver. Semin. Liver Dis. 4:193-206.
17. Genest, J.J.; Cohnjs, A.; Am, J. and Cardiol, (1995) 67:8.
18. Powers, A.C. (2005). Diabetes Mellitus. In: Kasper DL (ed). Harrison’s Principles of Internal medicine. 16th ed. Mc Graw- Hill companies. Inc.; Vol II: pp 2152-8
Published
2023-09-27
How to Cite
Sabar, Z. A., & Karim, F. (2023). Study of some biochemical parameters for patients withType II Diabetes Mellitus in Al Rifai district. Central Asian Journal of Medical and Natural Science, 4(5), 297-304. Retrieved from https://cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/1819
Section
Articles