Main Article Content

Abstract





Background: This study it has been successfully synthesized and characterized in the form of [3,4-dihydropyrimidin-2-(1H) ones] (1-3) a derivative. This compound were synthesized by reaction of 1,3-cyclohexane dione in the presence of ethanol, urea, and aromatic aldehyde(t-BuOK).It has been characterized spectroscopically (For example, 13C-NMR, 1H-NMR, and FT-IR) For the purpose of showing the chemical composition and the final result of the industrial compound.


Methods: The design of this research was cross-sectional. descriptive investigation,which included the preparation of a group of polypyrimidine derivatives.


Results: In the current work, 1,3-cyclohexandione, aromatic aldehydes, and urea are combined with ethanol to create 3,4-Dihydropyrimidine. The chemical composition of molecules was determined via spectral analysis (1-2)a.






Conclusion: When t-BuOK was used as a catalyst in this work to create three DHMP compounds, it produced outstanding results with a high yield and a quicker reaction time than the assistant factor.

Keywords

Biginilli reaction with 3,4-dihydropyrimidine-2-(1H)-ones

Article Details

How to Cite
Naser, L. A. (2023). Synthesis and Characterization of New 2-Thiophen 3’4-Dimethylbenzaldehyde as 3,4-Dihydropyrimidinone Derivatives. Central Asian Journal of Medical and Natural Science, 4(5), 33-37. Retrieved from https://cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/1778

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