Changes in the Biophysical Characteristics of Oral Fluid in Children with Type 1 Diabetes

  • Maxsumova S. S. Tashkent State Dental Institute
  • Maxsumova I. Sh. Tashkent State Dental Institute
  • Mukhamedova M. S. Tashkent State Dental Institute
  • Rakhmatullayeva D. U. Tashkent State Dental Institute
  • Khamidov I. S Tashkent State Dental Institute
Keywords: diabetes mellitus, mouth fluid, composition, viscosity, speed of salivation

Abstract

The article found that studies have identified biophysical aspects of oral fluid for children with type 1 diabetes, including changes in the rate of salivation rate, salivation volume, viscosity and pH. A significant increase in glucose levels disrupts the mineralization potential of solid tissues and mineralization processes, accelerates demineralization processes, increases the activity of microbial flora in the oral cavity, and leads to a violation of the balance of enzyme systems. In the later stages of endocrinopathy, a significant change in the pH level of oral fluid to acidosis indicates a weakening of buffer systems, a lack of functional capabilities and protective mechanisms of speech, and a disbalance in gomeostatic reactions in the oral cavity.

References

1. Makhsumova S. et al. Comprehensive Clinical Examination of the Oral Cavity in Children with Type 1 Diabetes Mellitus //Central Asian Journal of Medical and Natural Science. – 2022. – Т. 3. – №. 4. – С. 21-24.
2. Sanjarovna M. S., Shavkatovna M. I., Sagdullaevna M. M. CHANGES IN ORAL CAVITY OF CHILDREN WITH DIABETES //Journal of Pharmaceutical Negative Results. – 2022. – С. 2372-2377.
3. Badriddinovna D. S. et al. The Study Of The Immunological Properties Of Oral Fluid In Children With Type 1 Diabetes Mellitus //Journal of Pharmaceutical Negative Results. – 2022. – С. 1993-1995.
4. Даминова , Ш., Махсумова C., И. Махсумова, и З. Ахматова. «Оценка состояния гуморального и местного иммунитета полости рта у детей больных сахарным диабетом 1 типа». Stomatologiya, т. 1, вып. 4, июль 2023 г., сс. 62-65
5. Мухамедов И., et al. "МИКРОЭКОЛОГИЯ ПОЛОСТИ РТА У ДЕТЕЙ, БОЛЬНЫХ ГЕРПЕТИЧЕСКИМ СТОМАТИТОМ, ДО И ПОСЛЕ ЛЕЧЕНИЯ." Stomatologiya 1.2 (79) (2020): 63-66.
6. Мухамедова, М.С. and Рахматуллаева, Д.У., 2017. СОВРЕМЕННЫЕ АСПЕКТЫ ПРОФИЛАКТИКИ СТОМАТОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ У ДЕТЕЙ. Форум молодых ученых, (5 (9)), pp.1478-1483.
7. Gafforov, S., Khalimbetov, G., Nazarov, U., & Rahmatullaeva, D. (2022). DENTAL AND IMMUNOGENETIC FEATURES OF THE PATIENTS’BODY WITH UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA. EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE, 2(5), 144-152.
8. Нурматова, Н. Т., Каюмова, В. Р., Рахматуллаева, Д. У., & Ходжаева, Ф. Х. (2020). Научное обоснование применения биологически активных добавок на основе Ganoderma luсidum в комплексной профилактике кариеса зубов у детей. Стоматология детского возраста и профилактика, 20(1), 15-18.
Published
2023-09-06
How to Cite
Maxsumova S. S., Maxsumova I. Sh., Mukhamedova M. S., Rakhmatullayeva D. U., & Khamidov I. S. (2023). Changes in the Biophysical Characteristics of Oral Fluid in Children with Type 1 Diabetes. Central Asian Journal of Medical and Natural Science, 4(5), 6-10. https://doi.org/10.17605/cajmns.v4i5.1771
Section
Articles