Effect of Papilloma Virus on Some Immunological and Molecular Traits of Infected Women in Al-Diwaniyah Governorate

Taif Hussein  Ali; Habeeb Waseel Kadhim  Shubber

Taif Hussein Ali College of Science, University of Al-Qadisiyah, Iraq
Habeeb Waseel Kadhim Shubber College of Science, University of Al-Qadisiyah, Iraq

Keywords: Papilloma Virus, immune, molecular, infected women, Al-Diwaniyah Governorate

Abstract

The study was distracted by 70 samples were infected by Papilloma Virus, to study the effect of Papilloma Virus on some immune and molecular traits of infected people in Al-Qadisiyah Governorate, at 16 October 2022. The results indicated that the percentage of infection with the virus was 33.33%, compared to the non-infected, which amounted to 66.67%. The number of infected people in the urban was higher than in the rural. The age group 17-22 had the highest infection rate, which amounted to 46.15%, the lowest infection rate was in the age group 37-50, which amounted to 29.07%. The level of IL-10 and IL-1β was high in the age groups 17-26 and 27-36 years old, while the IgM was higher in the age group 37-50 years. The levels of IL-10, IL-1β and IgM were higher in the urban than in the rural. The C/T hybrid genotype has the lowest infection rate, compared to pure genotypes (C/C and T/T). There were no significant differences between the C and T alleles in the percentage of HIV infection.

References

1. Akarolo-Anthony, S.N., Famooto, A.O., Dareng, E.O. 2014. Age-specific prevalence of human papilloma virus infection among Nigerian women. BMC Public Health 14, 656.
2. Ardekani A, Taherifard E, Mollalo A, Hemadi E, Roshanshad A, Fereidooni R, Rouholamin S, Rezaeinejad M, Farid-Mojtahedi M, Razavi M, 2022. Human Papillomavirus Infection during Pregnancy and Childhood: A Comprehensive Review. Microorganisms. 10(10):1932.
3. Forman D, de Martel C, Lacey CJ, 2012. Global burden of human papillomavirus and related diseases. Vaccine, 30: Suppl 5:F12-F23.
4. Lewis RM, Laprise JF, Gargano JW. 2021. Estimated prevalence and incidence of disease-associated human papillomavirus types among 15- to 59-year-olds in the United States. Sex Transm Dis 2021; 48:273-277.
5. Mohammed, K.A., D.S. Subramaniam, C.J. Geneus, E.R. Henderson, C.A. Dean, D.P. Subramaniam and T.E. Burroughs. 2018. Rural-urban differences in human papillomavirus knowledge and awareness among US adults. Preventive Medicine, 109: 39-43.
6. Niyibizi, J.; Zanré, N.; Mayrand, M.-H.; Trottier, H. 2022. Association between Maternal Human Papillomavirus Infection and Adverse Pregnancy Outcomes: Systematic Review and Meta-Analysis. J. Infect. Dis. , 221, 1925-1937.
7. Schiffman M, Doorbar J, Wentzensen N, 2016. Carcinogenic human papillomavirus infection. Nat Rev Dis Primers, 2:16086.
8. Wang X, Huang X, Zhang Y. (2018). Involvement of human papillomaviruses in cervical cancer. In Frontiers in Microbiology (Vol. 9, Issue NOV).
9. Weyn, C.; Thomas, D.; Jani, J.; Guizani, M.; Donner, C.; Van Rysselberge, M.; Hans, C.; Bossens, M.; Englert, Y.; Fontaine, V. 2011.Evidence of human papillomavirus in the placenta. J. Infect. Dis., 203, 341-343.