Diagnostic Levels of Some Biochemical (RBS, Cholesterol, Triglyceride, HDL, VLDL, LDL, Urea, Creatinine and Total Protein) in Patients and Healthy Controls Subjects, Markers of Toxoplasma Infection in Patients with Acute Coronary Syndrome
Abstract
The current study was conducted to evaluate the current situation of the cardiac involvement due to the presence of Toxoplasma gondii infection in patients in Al-Diwaniyah City, Iraq. The present study enrolled randomly 120 patients with Acute coronary syndrome and 60 healthy control to surveillance Toxoplasma infection by monitored the dynamic changes of IgG findings and correlate that with myocarditis at different levels (age, gender, blood profiles of some features, and blood groups). The present results showed 42 (35.0%) of Acute coronary syndrome have active or previous Toxoplasma infection by finding positive results of IgG.
According to the blood profile, the mean levels of random blood sugar (RBS) were 221.46 ± 57.62 mg/dL, 203.73± 58.31 mg/dL, 108.60± 14.9 mg/dL and 93.3± 7.33 mg/dL, in Acute coronary syndrome patients with toxoplasmosis. Also the Mean levels of cholesterol were 227.56 ± 35.52, 202.90± 26.05, 162.06± 17.8 and 185.6 ± 8.1, Acute coronary syndrome patients with toxoplasmosis. Also the Mean levels of Triglyceride were 196.0± 70.31, 182.3± 54.86, 127.33± 19.9 and 126.83± 17.4, Acute coronary syndrome patients with toxoplasmosis.
References
2. Xue, M., Jiang, S., Qu, S., & Liu, H. (2019). Toxoplasma gondii infection and risk of ischemic heart disease: A systematic review and meta-analysis. Parasitology Research, 118(9), 2501-2509.
3. Koshy, A. A., Fouts, A. E., Lodoen, M. B., Alkan, O., Blau, H. M., & Boothroyd, J. C. (2010). Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions. Nature Methods, 7(4), 307-309.
4. Jalal, S., Khan, A. H., Iqbal, F., & Khan, H. A. (2016). Association of Toxoplasma gondii infection with ABO blood groups and Rh factor in pregnant women of Khyber Pakhtunkhwa, Pakistan. Journal of Parasitology Research, 2016, 1290176.
5. Fallahi, S., Kazemi, B., & Seyyed Tabaei, S. J. (2016). Blood groups and risk of toxoplasmosis: A systematic review and meta-analysis. Iranian Journal of Parasitology, 11(4), 451-460.
6. Montoya JG, Liesenfeld O. Toxoplasmosis. Lancet. 2004;363(9425):1965-1976.
7. Yazar S, Arman F, Yalçin S. A prevalence study on Toxoplasma infection in rural areas of Sivas Province, Turkey. BMC Public Health. 2004;4:66.
8. Flegr J, Prandota J, Sovičková M, et al. Toxoplasmosis--a global threat. Correlation of latent toxoplasmosis with specific disease burden in a set of 88 countries. PLoS One. 2014;9(3):e90203.
9. Liu Q, Wang ZD, Huang SY, et al. Seroprevalence of Toxoplasma gondii infection in the general population of Henan Province, China. Parasit Vectors. 2015;8:338.
10. Correa D, Saffioti S, da Silva PEP, et al. Relationship between toxoplasmosis and myocardial infarction: A systematic review and meta-analysis. PLoS One. 2017;12(2):e0172172.
11. Alvarado-Esquivel C, Liesenfeld O, Márquez-Conde JA, et al. Seroepidemiology of Toxoplasma gondii infection in drivers involved in road traffic accidents in the metropolitan area of Guadalajara, Jalisco, Mexico. BMC Infect Dis. 2007;7:103.
12. Havelaar AH, Kemmeren JM, Kortbeek LM. Disease burden of congenital toxoplasmosis. Clin Infect Dis. 2007;44(11):1467-1474.