The Impact of Some Physiological and Biochemical Variables on Children Suffering From Febrile Convulsion in Baghdad City
Abstract
The current study was conducted to study physiological and biochemical variables and their role in the occurrence of heat cramps in children in the city of Baghdad by measuring the percentage of complete blood count parameters, glutathione concentration, malondialdehyde concentration, and serum acetylcholine esterase enzyme. The number of samples in the current study was 90, which were divided into two groups: the control group which included 30 samples and the febrile convulsion group included 60 samples. The ages of the children ranged from 6 months to 60 months, and collecting samples from the Central Child Teaching Hospital in Baghdad\Al-Karkh for the period between 2 August until 15 November 2022, and the study concluded that there was a significant increase in the number of white blood cells, the percentage of lymphocytes, and the number of platelets, and a significant decrease in hemoglobin and acetylcholine esterase enzyme, and there was no significant difference in the number of red blood cells, the shape of red blood cells, the concentrations of glutathione, and malonedialdehyde.
References
2. Ellman, G.L., Courtney, K.D., Andres, V.Jr. and Featherstone, R.M. (1961). A new and rapid colorimetric determination of acetylcholinesterase activity. Bio.chem. Pharmacol; 7: 88-95.
3. Guidet , B .; Shah , S. ''Am. J. phsiol'' . 1989;257 (26): 440
4. Gupta, R.C. (2016). Kids Health, Febrile Seizures, .http://kidshealth.org/en/parents/febrile.html
5. Jarad,A. S., AL-Samawy,E. R. and AL-Badran,A. S. (2011). Effect of L-arginine on spermatogenesis of the diabetic rat. Bas J Vet Res; 10(2): 19-24.
6. Landreau-Mascaro, A.;Barret, B.; Mayau, M.J.; Tardieu, M.; and Blanche, S. (2002). Risk of early febrile seizure with perinatal exposure to nucleoside analogues. Lancet, 359(9306):583–4.
7. Lozoff, B.; Jimenez, E. and Smith, J.B. (2006). Double burden of iron deficiency in infancy and low socioeconomic status. Arch. Pediatr.Adoles.Med. 160:1108-12.
8. Matsuo, M.; Sasaki, K.;Ichimaru, T.;Nakazato, S.; and Hamasaki, Y. (2006). Increased IL-1beta production from dsRNA-stimulated leukocytes in febrile seizures. Pediatr. Neurol. 35(2):102-6.
9. Millichap, J.G.; and Millichap, J.J. (2006). Role of viral infections in the etiology of febrile seizures. Pediatr. Neurol. 35(3):165-72.
10. Pohanka M, Int. J. Mol. Sci., 15 (2014) 980912. Stella, V. J., Charman, W. N . and Naringrekar, V. H.Prodrugs. Do they have advantages in clinical practice? Drugs 29, 455–473 (1985).
11. Sadleir, LG.; andScheffer, IE. (2007). Febrile seizures. Brit. Med. J. 334(7588):307
12. Shinnar, S.; and Glauser, T.A. (2002). Febrile seizures. J. child.Neurol. 17(1suppl): S44-52.
13. Stafstrom, C.E. (2002). The incidence and prevalence of febrile seizures. In: Baram TZ, Shinnar S, editors. Febrile seizures. San Diego: Academic Press. pp. 1–25.
14. Swaiman, K.F.;Ashwal, S.;Shinnar, S.; and Ferriero. (2006).Febrile seizure Pediatric Neurology: principles and practice .4th ed. Philadelphia: Mosby Elsevier. p.1078-86.
15. Symptoms of febrile seizures. www.nhs.uk. 2012. Archived from the original on 6 October 2014. Retrieved 13 October 2014.
16. Vestergaard M.; Basso, O.;Henriksen, TB.;Ostergaard, JR.; and Olsen, J. (2002). Risk factors for febrile convulsions. Epidemiology,13(3):282-7.
17. Yadav D, Chandra J.Iron deficiency:beyond andanimia. Indian J Pediatr. 2011;78(1):65-72. [PubMed].