Relationship of Renal Dysfunction and Atrial Fibrillation in Chronic Heart Disease
Abstract
THE AIM of the study was to estimate relationship between atrial fibrillation (AF) and renal function, microalbuminuria. PATIENTS AND METHODS. 80 patients with CHF (44-male, 36-female, mean age 62 ±12 years) were evaluated. The cause of CHF in 15 (18,7%) patients was arterial hyperpressure, in 21 (26,2%)–IHD, in 44 (55%) their combination and 36 (45%) patients had myocardial infarction. 39 patients had persistent atrial fibrillation. The speed of glomerular filtration (SGF) was counted by MDRD formulae. Albumins in urine were counted by test-reagent strips. RESULTS. SGF was 65,4±17,6 ml/min/1,73 m2 and in 31 (38,7 %) patients it was<60 ml/min/1,73 m2. In most patients – 54 (67,5 %) of the left ventricular ejection fraction stayed the same (EF>50%). Patients with decreased kidney function had higher diameter of the left ventricular, mitral regurgitation. SGF was lower- 57,6±15,3 against 68,2±17,6 ml/min/1,73 m2, р<0,001 and albumins in urine were higher- 31,4±13,7 against 16,7±9,8 мг/л, р=0,02 in patients with AF, than without AF. CKD and functional class CHF were independently associated with atrial fibrillation. CONCLUSION. So, atrial fibrillation in CHF patients is associated with decrease glomerular filtration rate as well as with elevation of urinary albumin excretion compared to patients with sinus rhythm.
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