Effect of Combined Therapy of Atorvastatin with Milk Thistle Extract on the Functional State of the Liver in Patients with CHD
Keywords:
CHD, statins, milk thistle extract, liver, ALT, AST
Abstract
Coronary heart disease (CHD) remains the leading cause of death in industrialized countries and with a growing trend in developing countries. The most significant risk factor is hypercholesterolemia. While the most effective drug is statins. Statin therapy is usually well tolerated, but side effects may occur, including elevated liver enzymes, aminotransferases. In this regard, the appointment of statins, together with hepatoprotective drugs, such as: milk thistle extract reduces the side effects of lipid-lowering therapy in patients with CHD.
References
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3. Roffi M., Patrono C., Collet J.P., Mueller C., Valgimigli M., Andreotti F., et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J. 2016;37(3):267-315. doi: 10.1093/eurheartj/ehv320.
4. Shevchenko E.A. Such different hepatoprotectors // VetPharma. - 2015. - № 2 (24). -С. 28-31.
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Published
2022-12-07
How to Cite
Tokhirovna, B. N., Otakhanovich, Z. O., & Fayzullaevna, M. G. (2022). Effect of Combined Therapy of Atorvastatin with Milk Thistle Extract on the Functional State of the Liver in Patients with CHD. Central Asian Journal of Medical and Natural Science, 3(6), 301-304. https://doi.org/10.17605/cajmns.v3i6.1208
Section
Articles
