Neuro-Immune Features in Children with a Functional Constipation
Keywords:
children, functional constipation, chronic constipation, gastrointestinal tract
Abstract
The review details current views on the problem of functional constipation in children, discusses immune factors and their relationship with the nervous systemthat contribute to the formation of constipation. Рассмотрены Current data on the intestinal microbiota, which plays a major role in maintaining the body's immune balance, are reviewed, and pathogenetic and diagnostic principles of functional constipation in pediatric practice are described.
References
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17. Fayzullina R. A., & Belmer S. V. (2019). CHRONIC CONSTIPATION IN PEDIATRICIAN'S PRACTICE: WHAT DO WE KNOW? WHAT'S NEW?. Experimental and clinical gastroenterology, (11 (171)), 16-26.
18. Fedorova, O. V., Fedulova, E. N., Tutina, O. A., & Korkotashvili, L. V. (2011). Constipation in children: justification of correction of endogenous intoxication. Medical Almanac, (4), 195-199.
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23. Kwiatkowska M, Krogulska A. The significance of the gut microbiome in children with functional constipation. Adv Clin Exp Med. 2021 Apr;30(4):471-480. doi: 10.17219/acem/131215. PMID: 33908196.
24. Lewis M. L. et al. Prevalence of functional gastrointestinal disorders in children and adolescents. Th e Journal of pediatrics. – 2016, Vol. 177, pp.39–43. e3.
25. Robin S. G. et al. Prevalence of pediatric functional gastrointestinal disorders utilizing the Rome IV criteria. The Journal of pediatrics. – 2018, Vol. 195, pp.134–139.
26. Shea-Donohue T, Urban JF Jr. Neuroimmune Modulation of Gut Function. Handb Exp Pharmacol. 2017; 239:247-267. doi: 10.1007/164_2016_109. PMID: 28035531.
27. Vandenplas Y. et al. Functional gastro‐intestinal disorder algorithms focus on early recognition, parental reassurance and nutritional strategies. Acta Paediatrica. – 2016, Vol. 105, no.3, pp.244–252.
28. Vandenplas Yvan, Levy Elvira, Lemmens Roel, Devreker Thierry Functional constipation in children // Pediatrics. Appendix to the journal Consilium Medicum. 2017. No. 1. URL: https://cyberleninka.ru/article/n/funktsionalnyy-zapor-u-detey://cyberleninka.ru/article/n/funktsionalnyy-zapor-u-detey (accessed: 24.08.2021).
29. Verburg-van Kemenade BM, Cohen N, Chadzinska M (2017) Neuroendocrine-immune interaction: evolutionarily conserved mechanisms that maintain allostasis in an ever-changing environment. Dev Comp Immunol 66:2–23
30. Khamraeva D. R // Functional constipation in children and its neuro-immune feature: Special issue on COVID-19: Yesterday, Today, and Tomorrow р.243-248
31. Zhang YC, Chen BX, Xie XY, Zhou Y, Qian Q, Jiang CQ. Role of Tenascin-X in regulating TGF-β/Smad signaling pathway in pathogenesis of slow transit constipation. World J Gastroenterol. 2020 Feb 21;26(7):717-724. doi: 10.3748/wjg.v26.i7.717. PMID: 32116419; PMCID: PMC7039833.
2. Gasilina T. V., Belmer S. V. Issues of drug therapy for constipation of functional origin in children. Medical advice. 2015; 4: 54–58. / Gasilina T.V., Bel'mer S.V. Voprosy medikamentoznoj terapii zaporov funktsional'nogo proiskhozhdeniya u detej. Meditsinskij sovet. – 2015. – № 4. – S. 54–58. [in Russian]
3. Grigoriev K. I. CONSTIPATION IN CHILDREN // Medical nurse. 2014. No. 2. URL: https://cyberleninka.ru/article/n/zapory-u-detey-3 (accessed: 24.08.2021).
4. Denisov M. Yu.,Natal Шведкинаfactors in the genesis of functional diseases of the digestive tract in infants and measures for their prevention. Bulletin of the Novosibirsk State University. Series: Biology, Clinical Medicine 2012; 10: 4: 102-111.
5. Dicheva D. T., Andreeva D. N. Irritable bowel syndrome: new aspects of pathophysiology and therapy. Доктор.ру. 2011;X. [D.T. Dicheva, D.N. Andreeva, Irritable bowel syndrome: new aspects of pathophysiology and therapy. Doctor.ru. 2011;X.] (In Russ)
6. Dubrovskaya M. I. Current state of the problem of functional disorders of the digestive tract in young children //Questions of modern pediatrics. - 2013. - Vol. 12. - no . 4. - p. 26-31
7. Il'enkova N. A., & V. V. Chikunov (2013). Functional constipation in children and adolescents. Bulletin of the Clinical Hospital No. 51, V (5 (2)), 100-107.
8. Katkovskaya A. A., Gorchakov V. N., Gaskina T. K. Limfotropnye tekhnologii korrektsii v eksperimental'noi gastroenterologii [Lymphotropic correction technologies in experimental gastroenterology]. Bulletin of the Siberian Branch of the Russian Academy of Medical Sciences, 2009, no. 3, pp. 20-28.
9. Komarova O. N., Khavkin A. I. Algorithm of examination and treatment of young children with constipation. Russian Medical Journal, 2016, vol. 24, No. 6, pp. 358-360 / Komarova O..N., Khavkin A..I. Algoritm obsledovaniya i lecheniya detejrannego vozrasta s zaporami. Russkij meditsinskij zhurnal. 2016; 24: 6: 358–360. [in Russian]
10. Moskalets O. V., & Shcherbina V. I. (2016). Features of the immune response in chronic constipation in children. Kuban Scientific Medical Bulletin, (2), 119-121.
11. Nikolaeva Svetlana Viktorovna, & Gorelov Alexander Vasilyevich (2019). Treatment and prevention of functional constipation in children. Difficult Patient, 17 (1-2), 37-41. doi: 10.24411/2074-1995-2019-10006
12. Privorotsky, V. F., & Luppova, N. E. (2010). Chronic functional constipation in children: from understanding the problem to adequate treatment. Voprosy sovremennoi pediatrii [Issues of Modern Pediatrics], 9 (6), 69-77.
13. Rivkin V. L. Khronicheskie zapory [Chronic constipation]. https://cyberleninka.ru/article/n/hronicheskie-zapory (accessed: 24.08.2021).
14. Serebryakova E. N. (2020). Constipation in children: the role of probiotics in prevention and treatment. The Difficult Patient, 18 (1-2), 53-56. doi: 10.24411 / 2074-1995-2020-10010
15. Sitnikova Elena Pavlovna (2013). Functional constipation in infants and young children. Russian Bulletin of Perinatology and Pediatrics, 58 (6), 102-106.
16. Ursova, N. I. (2010). Functional constipation in young children: rational management tactics. Practical Medicine, (45), 55-60.
17. Fayzullina R. A., & Belmer S. V. (2019). CHRONIC CONSTIPATION IN PEDIATRICIAN'S PRACTICE: WHAT DO WE KNOW? WHAT'S NEW?. Experimental and clinical gastroenterology, (11 (171)), 16-26.
18. Fedorova, O. V., Fedulova, E. N., Tutina, O. A., & Korkotashvili, L. V. (2011). Constipation in children: justification of correction of endogenous intoxication. Medical Almanac, (4), 195-199.
19. Tsymbalova, E. G. (2011). Chronic constipation in children. Voprosy sovremennoi pediatrii[Issues of Modern Pediatrics], 10 (2), 173-179.
20. Shcherbakov P. L., Medvedev B. A. Prevention and treatment of constipation in children. Effective pharmacotherapy. – 2015. – № 42. – С. 14–18. / Shcherbakov P.L., Medvedev B.A. Profilaktika i lechenie zaporov u detej. Effektivnaya farmakoterapiya. 2015; 42: 14–18. [in Russian]
21. Beaudry-Bellefeuille I., Booth D., Lane S. J. Defecationspecifi c behavior in children with functional defecation issues: A systematic review. Th e Permanente Journal. – 2017, Vol. 21, pp.17–47
22. Benninga MA, Nurko S, Faure C et al. Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology. 2016; 150: 1443–55.
23. Kwiatkowska M, Krogulska A. The significance of the gut microbiome in children with functional constipation. Adv Clin Exp Med. 2021 Apr;30(4):471-480. doi: 10.17219/acem/131215. PMID: 33908196.
24. Lewis M. L. et al. Prevalence of functional gastrointestinal disorders in children and adolescents. Th e Journal of pediatrics. – 2016, Vol. 177, pp.39–43. e3.
25. Robin S. G. et al. Prevalence of pediatric functional gastrointestinal disorders utilizing the Rome IV criteria. The Journal of pediatrics. – 2018, Vol. 195, pp.134–139.
26. Shea-Donohue T, Urban JF Jr. Neuroimmune Modulation of Gut Function. Handb Exp Pharmacol. 2017; 239:247-267. doi: 10.1007/164_2016_109. PMID: 28035531.
27. Vandenplas Y. et al. Functional gastro‐intestinal disorder algorithms focus on early recognition, parental reassurance and nutritional strategies. Acta Paediatrica. – 2016, Vol. 105, no.3, pp.244–252.
28. Vandenplas Yvan, Levy Elvira, Lemmens Roel, Devreker Thierry Functional constipation in children // Pediatrics. Appendix to the journal Consilium Medicum. 2017. No. 1. URL: https://cyberleninka.ru/article/n/funktsionalnyy-zapor-u-detey://cyberleninka.ru/article/n/funktsionalnyy-zapor-u-detey (accessed: 24.08.2021).
29. Verburg-van Kemenade BM, Cohen N, Chadzinska M (2017) Neuroendocrine-immune interaction: evolutionarily conserved mechanisms that maintain allostasis in an ever-changing environment. Dev Comp Immunol 66:2–23
30. Khamraeva D. R // Functional constipation in children and its neuro-immune feature: Special issue on COVID-19: Yesterday, Today, and Tomorrow р.243-248
31. Zhang YC, Chen BX, Xie XY, Zhou Y, Qian Q, Jiang CQ. Role of Tenascin-X in regulating TGF-β/Smad signaling pathway in pathogenesis of slow transit constipation. World J Gastroenterol. 2020 Feb 21;26(7):717-724. doi: 10.3748/wjg.v26.i7.717. PMID: 32116419; PMCID: PMC7039833.
Published
2022-08-30
How to Cite
I. , N. S., & R., K. D. (2022). Neuro-Immune Features in Children with a Functional Constipation. Central Asian Journal of Medical and Natural Science, 3(4), 367-373. https://doi.org/10.17605/cajmns.v3i4.1037
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