Clinical Aspects of Treatment of Breast Cancer Patients with Metastatic Lymph Nodes Injury

  • Almuradova D. M. Tashkent Medical Academy
  • Odilova Sh. Sh Tashkent Medical Academy
  • Ubaydullaev I. A. Tashkent Medical Academy
  • Islomov S. D Tashkent Medical Academy
  • Sharobiddinov B. B. Tashkent Medical Academy
Keywords: metastasis, ipsilateral supraclavicular lymph nodes, locally advanced breast cancer, locoregional recurrence

Abstract

It is generally accepted that one of the most significant prognostic factors determining the outcome of the disease is the presence of tumor metastases in regional lymph nodes. Despite the fact that the assessment of the true extent of the process at the stage of clinical diagnosis is extremely important for determining the appropriate treatment tactics, standard research methods do not always allow to reliably assess the possible metastatic lesion of the lymphatic collectors. The only reliable and significant method for diagnosing lymphogenous metastasis is a morphological examination of lymph nodes, since modern research methods (echography, computed and magnetic resonance imaging, radionuclide diagnostics) cannot give a clear answer about the presence or absence of metastases in the lymph nodes.

References

1. Ismagilov, A.Kh. Surgical treatment of breast cancer of central and medial localizations / A.Kh Ismagilov, E.I. Sigal. — Kazan, 2004. — 165 p.
2. Minimum clinical guidelines of the European Society for Medical Oncology (ESMO) .— M., 2004
3. Practical mammology / I.V. Vysotskaya, N.E. Kushlinsky, E.M. Pogodin and [others]. - M .: Practical medicine, 2007. - 271 p.
4. Andreassen, M Exten ded exeresis of the regional lymph nodes at operation for carcinoma of the breast and result of a 5-year follow-up of the first 98 cases with removal of the axillary as well as the supraclavicular glands / M Andreassen, E. Dahl-Iversen, B. Soerensen // Acta chir. scand. — 1954 — Vol. 107 (2-3) .— P. 206-213.
5. Ciardiello, F. A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor / F. Ciardiello, G. Tortora // Clin. Cancer Res. 2001. Vol. 7 (10). - P.2958-2970.
6. Long-term results of combined-modality therapy for locally advanced breast cancer with ipsilateral supraclavicular metastases: The University of Texas M.D. Anderson Cancer Center experience / R.A. Brito, V. Valero, A.U. Buzdar [et al.] // J. Clin. Oncol. — 2001, —Vol.19. — P.628— 633.
7. Long-term survival of patients with supraclavicular metastases at diagnosis of breast cancer / I.A. Olivotto, B. Chua, S.J. Allan [et al.] // Journal of Clinical Oncology. — 2003. — Vol. 21, —P.851—854.
Published
2021-10-21
How to Cite
M., A. D., Sh, O. S., A., U. I., D, I. S., & B., S. B. (2021). Clinical Aspects of Treatment of Breast Cancer Patients with Metastatic Lymph Nodes Injury. Central Asian Journal of Medical and Natural Science, 2(5), 290-293. https://doi.org/10.17605/cajmns.v2i5.380
Section
Articles

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