CYTOKINE PROFILE OF BLOOD PLASMA AND ORAL FLUID IN PREGNANT WOMEN WITH ODONTOGENIC INFLAMMATORY DISEASES

  • Kakhramon Erkinovich Shomurodov Associate Professor, Department of Oral and Maxillofacial Diseases and Injuries Tashkent State Dental Institute
  • Miraskad Maksudovich Isomov Assistant Professor, Department of Oral and Maxillofacial Diseases and Injuries Tashkent State Dental Institute
Keywords: blood plasma, pregnant women, cytokinеprofile, diseases, odontogenic inflammatory

Abstract

This article is devoted to the study of the cytokine profile of blood serum and oral fluid, as well as the level of mucosal immunity in pregnant women with odontogenic inflammatory diseases of the maxillofacial region.

It was revealed that a comprehensive assessment of the condition of pregnant women indicates a combined effect of adverse factors on the oral cavity tissues, namely: a low level of oral hygiene, a decrease in the functional activity of the salivary glands, accompanied by a change in the properties of the secretion, in particular, the surface tension of saliva; suppression of local mucosal immunity of the mouth; increased degree of microbial contamination.

References

Lazanovich V.A., Smirnov G.A., Markelova E.V., Silich E.V., Semekhin A.I., Koryavchenkova I.V. Roncoleukin in treatment of septic patients //Medical Immunology. - 2000. - Т. 2, № 2.- С. 224.

Shomurodov K.E. Peculiarities of cytokine balance in gingival fluid at odontogenicphlegmon of maxillofacial area // The doctor-aspirant. - 2010. - 42(5.1). - С. 187-192.

Isomov M.M., Shomurodov K.E. Peculiarities of rehabilitation of pregnant women with inflammatory diseases of maxillofacial area // International scientific-practical conference "Modern aspects of complex dental rehabilitation of patients with maxillofacial defects" May 21-22, 2020, Krasnodar. - 2020. - С. 72-76.

DeKruyff F., Fang Y., Secrist H., Umetsu D. IL-4 synthesis by in vivo primed memory CD4+T-cells // J. Clin.Immunol. – 2005. – Vol. 15. – P. 105-115.

Isomov M.M., Shomurodov K.E., Olimjonov K.J., Azimov I.M. Features of etiopathogenesis and the course of inflammatory processes of periapical tissues in women during pregnancy (review of literature) // Биомедицинаваамалиётжурнали. – 2020. – №SI-2. – С. 833-838.

Mallat Z., Besnard S., Duriez M., Deleuze V., Emmanuel F., Bureau M.F, Soubrier F., Esposito B., Duez H., Fievet C., Staels B., Duverger N. Protective role of interleukin-10 in atherosclerosis // Circ. Res. – 2009. – Vol. 85. – P. 17-24.

Martinez O.M., Gibbons R.S., Garovoy M.R., Aronson F.R. IL-4 inhibits IL-2 receptor expression and IL-2-dependent proliferation of human T-cells // J. Immunol. – 2001. – Vol. 144. – P. 2211-2215.

Musaev U.Y.,Rizaev J.A., Shomurodov K.E. New views on the problem of dysemryogenesis stigmas of dento-mandibular and facial system from the position of their formation in the disability of the population // Central Asian Scientific and Practical Journal "Stomatologiya "2017.-#3-(68).-P.9-12.

Shomurodov. K.E. Features of cytokine balance in gingival fluid at odontogenicphlegmon of maxillofacial area. // Doctor-aspirant 2010.-42 Vol.-No.5.1.-P.187-192;

Published
2021-05-26
How to Cite
Kakhramon Erkinovich Shomurodov, & Miraskad Maksudovich Isomov. (2021). CYTOKINE PROFILE OF BLOOD PLASMA AND ORAL FLUID IN PREGNANT WOMEN WITH ODONTOGENIC INFLAMMATORY DISEASES. Central Asian Journal of Medical and Natural Science, 2(3), 118-122. https://doi.org/10.17605/cajmns.v2i3.183
Section
Articles